Giriş: Çalışmamızda fetal abdomen çevresi ölçümü ile omuz distosisi arasında herhangi bir ilişki olup olmadığı araştırılmıştır. Materyal-Metod: Çalışmamız retrospektif bir çalışmadır. Hastanemizde 2013-2023 yılları arasında doğum yapmış hastalar çalışmaya alınmıştır. Vajinal doğum yapmış 100 vaka ve 100 kontrol grubu olmak üzere toplam 200 hasta çalışmaya alınmıştır. Fetal abdomen çevresi ile omuz distosisi arasındaki ilişki irdelenmiştir. Çalışmamızın istatistik analizi için SPSS (IBM SPSS for Windows, Ver.26) istatistik paket programı kullanılmıştır. Bulgular: Çalışmamız toplam 200 gebe üzerinde yapılmıştır. Hastaların yaş ortalaması 28.1±5.6’dir. Gebelerin fetal abdomen çevresi ultrason ölçüm değeri ortalaması 36.3+1.3 cm’dir. Çalışmamızda ultrasonda fetal abdomen çevresi ölçümü 37.27±0.5 cm ve üzeri olan grupta omuz distosisi görülme oranı kontrol grubuna kıyasla istatiksel olarak anlamlı yüksek saptanmıştır (p=0.000). Çalışmamızda vaka grubu ile kontrol grubu arasında fetal ağırlık ile omuz distosisi arasında istatiksel olarak anlamlı bir ilişki saptanmamıştır (p=0.235). Omuz distosisi görülen gebelerde görülmeyen gebelere kıyasla fetal komplikasyon görülme oranları istatiksel olarak anlamlı yüksek bulunmuştur (p=0.000). Yine omuz distosisi görülen gebelerde görülmeyen gebelere kıyasla maternal komplikasyon görülme oranları istatiksel olarak anlamlı yüksek bulunmuştur (p=0.001). Sonuç: Çalışmamızın sonucunda ultrasonda fetal abdomen çevresi ölçümü 37.27±0.5 cm ve üzeri olan grupta omuz distosisi görülme oranı kontrol grubuna kıyasla anlamlı derecede yüksek bulunmuştur.
{"title":"Fetal Abdomen Çapı Ölçümü ile Omuz Distosisi Arasındaki İlişkinin İncelenmesi-Retrospektif Vaka Kontrol Çalışması","authors":"İsa Kaplan, Mesut Saka","doi":"10.38136/jgon.1415984","DOIUrl":"https://doi.org/10.38136/jgon.1415984","url":null,"abstract":"Giriş: Çalışmamızda fetal abdomen çevresi ölçümü ile omuz distosisi arasında herhangi bir ilişki olup olmadığı araştırılmıştır. \u0000Materyal-Metod: Çalışmamız retrospektif bir çalışmadır. Hastanemizde 2013-2023 yılları arasında doğum yapmış hastalar çalışmaya alınmıştır. Vajinal doğum yapmış 100 vaka ve 100 kontrol grubu olmak üzere toplam 200 hasta çalışmaya alınmıştır. Fetal abdomen çevresi ile omuz distosisi arasındaki ilişki irdelenmiştir. Çalışmamızın istatistik analizi için SPSS (IBM SPSS for Windows, Ver.26) istatistik paket programı kullanılmıştır. \u0000Bulgular: Çalışmamız toplam 200 gebe üzerinde yapılmıştır. Hastaların yaş ortalaması 28.1±5.6’dir. Gebelerin fetal abdomen çevresi ultrason ölçüm değeri ortalaması 36.3+1.3 cm’dir. Çalışmamızda ultrasonda fetal abdomen çevresi ölçümü 37.27±0.5 cm ve üzeri olan grupta omuz distosisi görülme oranı kontrol grubuna kıyasla istatiksel olarak anlamlı yüksek saptanmıştır (p=0.000). Çalışmamızda vaka grubu ile kontrol grubu arasında fetal ağırlık ile omuz distosisi arasında istatiksel olarak anlamlı bir ilişki saptanmamıştır (p=0.235). Omuz distosisi görülen gebelerde görülmeyen gebelere kıyasla fetal komplikasyon görülme oranları istatiksel olarak anlamlı yüksek bulunmuştur (p=0.000). Yine omuz distosisi görülen gebelerde görülmeyen gebelere kıyasla maternal komplikasyon görülme oranları istatiksel olarak anlamlı yüksek bulunmuştur (p=0.001). \u0000Sonuç: Çalışmamızın sonucunda ultrasonda fetal abdomen çevresi ölçümü 37.27±0.5 cm ve üzeri olan grupta omuz distosisi görülme oranı kontrol grubuna kıyasla anlamlı derecede yüksek bulunmuştur.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":" 41","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amaç: Türkiye 2022 yılı itibarı ile sezaryen oranında Dünya’da ilk sıraya konumlanmıştır. Bu çalışma Türkiye’deki sezaryen ve normal doğum ile ilgili mevcut durumu ortaya koymak ve politika önerilerinde bulunmak amacıyla yapılmıştır. Gereçler ve Yöntem: Çalışmada kullanılan veriler Sağlık Bakanlığı istatistik yıllıkları, Eurostat ve OECD veri tabanlarından, Sağlık Bakanlığı ve Sosyal Güvenlik Kurumu ilgili birimlerinin web sitelerinden temin edilmiş olup kamuoyuna açık verilerdir. Çalışma temin edilen veriler kapsamında kendi içinde Türkiye bölgeleri ve uluslararası düzeyde karşılaştırmalı analizi yapılmış, aynı zamanda literatür ile de tartışılmıştır. Bulgular: Türkiye sezaryen oranı açısından Dünya’da ilk sıradadır, özel sektörse sezaryen oranı %78,1’çıkmıştır. Türkiye’de bölgeler arasında sezaryen oranları arasında farklılıklar yüksektir. Sağlık Bakanlığı ve Sosyal Güvenlik Kurumu’nun caydırıcı düzenlemelerine rağmen sezaryen oranları Türkiye’de artma eğilimini devam ettirmiştir. Sonuç: Türkiye sezaryen oranlarını düşürmeye yönelik olarak; başarılı ülkelerin uygulamalarını değerlendirmeli, kanıta dayalı rehber ve protokoller kapsamında doğum sürecini yürütmeli, sezaryen ameliyatını maliyet unsuru yapmak yerine toplumu anne ve bebek sağlığı açısından normal doğuma yönelik aydınlatmalıdır. Sağlık ve ödeme sistemlerinde sezaryene yönelik bütünleşik yönetim mekanizması oluşturmalıdır.
{"title":"TÜRKİYE SEZARYEN ORANI DURUM ANALİZİ VE POLİTİKA ÖNERİLERİ","authors":"Gülsen Topaktaş, Umut Beylik","doi":"10.38136/jgon.1482889","DOIUrl":"https://doi.org/10.38136/jgon.1482889","url":null,"abstract":"Amaç: Türkiye 2022 yılı itibarı ile sezaryen oranında Dünya’da ilk sıraya konumlanmıştır. Bu çalışma Türkiye’deki sezaryen ve normal doğum ile ilgili mevcut durumu ortaya koymak ve politika önerilerinde bulunmak amacıyla yapılmıştır. \u0000Gereçler ve Yöntem: Çalışmada kullanılan veriler Sağlık Bakanlığı istatistik yıllıkları, Eurostat ve OECD veri tabanlarından, Sağlık Bakanlığı ve Sosyal Güvenlik Kurumu ilgili birimlerinin web sitelerinden temin edilmiş olup kamuoyuna açık verilerdir. Çalışma temin edilen veriler kapsamında kendi içinde Türkiye bölgeleri ve uluslararası düzeyde karşılaştırmalı analizi yapılmış, aynı zamanda literatür ile de tartışılmıştır. \u0000Bulgular: Türkiye sezaryen oranı açısından Dünya’da ilk sıradadır, özel sektörse sezaryen oranı %78,1’çıkmıştır. Türkiye’de bölgeler arasında sezaryen oranları arasında farklılıklar yüksektir. Sağlık Bakanlığı ve Sosyal Güvenlik Kurumu’nun caydırıcı düzenlemelerine rağmen sezaryen oranları Türkiye’de artma eğilimini devam ettirmiştir. \u0000Sonuç: Türkiye sezaryen oranlarını düşürmeye yönelik olarak; başarılı ülkelerin uygulamalarını değerlendirmeli, kanıta dayalı rehber ve protokoller kapsamında doğum sürecini yürütmeli, sezaryen ameliyatını maliyet unsuru yapmak yerine toplumu anne ve bebek sağlığı açısından normal doğuma yönelik aydınlatmalıdır. Sağlık ve ödeme sistemlerinde sezaryene yönelik bütünleşik yönetim mekanizması oluşturmalıdır.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":" 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141368035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z. Ağaoğlu, A. Tanaçan, Betül Akgün Aktaş, Esra Karataş, G. Okutucu, Hakkı Şerbetçi, Özgür Kara, Dilek Sahin
Objective: To investigate whether the fibrinogen-to-albumin ratio (FAR.) could predict the severity of disease in hyperemesis gravidarum (HG). Materials and Methods: This study was designed prospectively at a single tertiary center and included a total of 283 patients with HG. The patients were divided into the following groups based on the severity of the disease evaluated using the Pregnancy-Unique Quantification of Emesis scoring system: mild HG (n=144) (score6), moderate HG (n=80) (score: 7-12), and severe HG (n=59) (score13). FAR was calculated by dividing fibrinogen by albumin. Results: There was a significant difference between the HG groups in terms of the gestational week at disease onset (p
{"title":"Assessment of the Fibrinogen-to-Albumin Ratio in Predicting the Severity of Hyperemesis Gravidarum","authors":"Z. Ağaoğlu, A. Tanaçan, Betül Akgün Aktaş, Esra Karataş, G. Okutucu, Hakkı Şerbetçi, Özgür Kara, Dilek Sahin","doi":"10.38136/jgon.1457845","DOIUrl":"https://doi.org/10.38136/jgon.1457845","url":null,"abstract":"Objective: To investigate whether the fibrinogen-to-albumin ratio (FAR.) could predict the severity of disease in hyperemesis gravidarum (HG). \u0000Materials and Methods: This study was designed prospectively at a single tertiary center and included a total of 283 patients with HG. The patients were divided into the following groups based on the severity of the disease evaluated using the Pregnancy-Unique Quantification of Emesis scoring system: mild HG (n=144) (score6), moderate HG (n=80) (score: 7-12), and severe HG (n=59) (score13). FAR was calculated by dividing fibrinogen by albumin. \u0000Results: There was a significant difference between the HG groups in terms of the gestational week at disease onset (p","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":" 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141373586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: Adnexal mass is one of the most common surgical indications in gynecology clinics, and laparoscopy is generally accepted as a gold standard in the management of adnexal mass. Materials and Method: Single incision laparoscopic surgery (SILS) is an evolving endoscopic approach in the era of minimal access surgery. Recently, it has been reported that adnexal mass may also be managed by SILS. In this report, we present 3 symptomatic patients with a huge adnexal mass operated by a single port laparoscopic approach. Results: The mean duration of the operations 95 minutes (range 75-135 minutes). None of the patients converted to laparotomy. All patients discharged on postoperative day 1. None of the patients required readmission to the hospital. Postoperatively all patients were satisfied with their incision and cosmetic results. Conclusion: Single port laparoscopic management can be successfully completed via SILS PortTM in patients with large adnexal masses with better cosmetic outcomes.
{"title":"Huge Adnexal Masses Managed by Single Port Laparoscopy: A case series","authors":"Gonca Türker Ergün, T. Arslanca, Polat Dursun","doi":"10.38136/jgon.1441340","DOIUrl":"https://doi.org/10.38136/jgon.1441340","url":null,"abstract":"Aim: Adnexal mass is one of the most common surgical indications in gynecology clinics, and laparoscopy is generally accepted as a gold standard in the management of adnexal mass. Materials and Method: Single incision laparoscopic surgery (SILS) is an evolving endoscopic approach in the era of minimal access surgery. Recently, it has been reported that adnexal mass may also be managed by SILS. In this report, we present 3 symptomatic patients with a huge adnexal mass operated by a single port laparoscopic approach. \u0000Results: The mean duration of the operations 95 minutes (range 75-135 minutes). None of the patients converted to laparotomy. All patients discharged on postoperative day 1. None of the patients required readmission to the hospital. Postoperatively all patients were satisfied with their incision and cosmetic results. \u0000Conclusion: Single port laparoscopic management can be successfully completed via SILS PortTM in patients with large adnexal masses with better cosmetic outcomes.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"7 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141101258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hüseyin Erdinç Karakaş, Merve Çakır Karakaş, Mehmet Ferdi Kıncı, Tuğba Altun Ensari
Aim: This study aimed to compare the inflammatory markers in patients who had ovulation induction with clomiphene citrate (CC) and who underwent intrauterine insemination (IUI) due to unexplained infertility in patients who could get pregnant and who could not. Materials and Method: The study included 125 females with unexplained infertili-ty who underwent ovulation induction with CC and who underwent IUI at the Health Sciences University Ankara Etlik Zübeyde Hanım Gynecology Training and Research Hospital Assisted-Reproduction Therapy Clinic between July 2019 and December 2019. Of the patients, 104 (83.2%) of them could not get pregnant as a result of IUI, and 21 (16.8%) females got pregnant. Hemogram parameters collected from patients on the day of IUI were recorded. Results: In terms of age, infertility duration, BMI, gravida, parity, number of living children, abortion and stillbirth numbers, no statistically significant difference was found between the two patient groups which were created based on getting pregnant or not (p>0.05). No significant difference was found between the groups in terms of serum estrogen, progesterone, follicle-stimulating hormone (FSH), luteinizing hor-mone (LH), thyroid stimulating hormone (TSH), prolactin, and anti-mullerian hor-mone (AMH) levels, hemoglobin, BM, neutrophil count, lymphocyte count, platelet count, MPV, CRP, and P/L ratio (p>0.05). A statistically significant difference was found in terms of N/L ratio (p
{"title":"Evaluation of Inflammation Markers and Pregnancy Outcomes of Patients Undergoing Intrauterin Insemination (IUI) for Unexplained Infertility","authors":"Hüseyin Erdinç Karakaş, Merve Çakır Karakaş, Mehmet Ferdi Kıncı, Tuğba Altun Ensari","doi":"10.38136/jgon.1415177","DOIUrl":"https://doi.org/10.38136/jgon.1415177","url":null,"abstract":"Aim: This study aimed to compare the inflammatory markers in patients who had ovulation induction with clomiphene citrate (CC) and who underwent intrauterine insemination (IUI) due to unexplained infertility in patients who could get pregnant and who could not. \u0000Materials and Method: The study included 125 females with unexplained infertili-ty who underwent ovulation induction with CC and who underwent IUI at the Health Sciences University Ankara Etlik Zübeyde Hanım Gynecology Training and Research Hospital Assisted-Reproduction Therapy Clinic between July 2019 and December 2019. Of the patients, 104 (83.2%) of them could not get pregnant as a result of IUI, and 21 (16.8%) females got pregnant. Hemogram parameters collected from patients on the day of IUI were recorded. \u0000Results: In terms of age, infertility duration, BMI, gravida, parity, number of living children, abortion and stillbirth numbers, no statistically significant difference was found between the two patient groups which were created based on getting pregnant or not (p>0.05). No significant difference was found between the groups in terms of serum estrogen, progesterone, follicle-stimulating hormone (FSH), luteinizing hor-mone (LH), thyroid stimulating hormone (TSH), prolactin, and anti-mullerian hor-mone (AMH) levels, hemoglobin, BM, neutrophil count, lymphocyte count, platelet count, MPV, CRP, and P/L ratio (p>0.05). A statistically significant difference was found in terms of N/L ratio (p","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141111533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nihat Farisoğulları, A. Tanaçan, Bedri Sakcak, Ramazan Denizli, Özgür Kara, Dilek Sahin
Aim: To investigate the role of the fetal modified myocardial performance index (Mod-MPI) and fetal cardiac output index measurement in predicting adverse perinatal outcomes among preterm dichorionic twins. Materials and Method: This prospective cohort study was conducted at the X Clinic and included 34 dichorionic twin fetuses born early preterm and 40 dichorionic twin fetuses born late preterm. The early preterm group was divided into two according to whether they were admitted to the neonatal intensive care unit (NICU). The groups' cardiac function and Mod-MPI measurements were compared regarding their predictive ability for adverse perinatal outcomes. Results: The Mod-MPI values were similar between the early and late preterm groups (p=0.144). The left ventricular cardiac output Z-score was lower in the preterm group (p=0.014). The Mod-MPI and left ventricular outflow tract-isovolumetric contraction and isovolumetric relaxation times were significantly higher among the newborns admitted to the NICU in the early preterm group (p=0.002, p=0.003, and p=0.001, respectively). Conclusion: Our study suggests that the Mod-MPI measurement can be used to predict adverse perinatal outcomes in dichorionic twin fetuses born in the early preterm period.
目的：研究胎儿改良心肌表现指数（Mod-MPI）和胎儿心输出量指数测量在预测早产二绒毛膜双胎围产期不良结局中的作用。材料与方法：这项前瞻性队列研究在 X 诊所进行，包括 34 个早产的二绒毛膜双胎和 40 个晚期早产的二绒毛膜双胎。早产组根据是否进入新生儿重症监护室（NICU）分为两组。比较了各组的心功能和Mod-MPI测量结果对围产期不良结局的预测能力。结果早产组和晚期早产组的 Mod-MPI 值相似（P=0.144）。早产组的左心室心输出量 Z 评分较低（P=0.014）。早产儿早期组新生儿的 Mod-MPI、左室流出道等容收缩时间和等容舒张时间显著高于新生儿重症监护室（分别为 p=0.002、p=0.003 和 p=0.001）。结论我们的研究表明，Mod-MPI 测量可用于预测早产早期二绒毛膜双胎的围产期不良结局。
{"title":"Role of fetal cardiac assessment in predicting adverse perinatal outcomes in preterm dichorionic twins","authors":"Nihat Farisoğulları, A. Tanaçan, Bedri Sakcak, Ramazan Denizli, Özgür Kara, Dilek Sahin","doi":"10.38136/jgon.1452184","DOIUrl":"https://doi.org/10.38136/jgon.1452184","url":null,"abstract":"Aim: To investigate the role of the fetal modified myocardial performance index (Mod-MPI) and fetal cardiac output index measurement in predicting adverse perinatal outcomes among preterm dichorionic twins. \u0000Materials and Method: This prospective cohort study was conducted at the X Clinic and included 34 dichorionic twin fetuses born early preterm and 40 dichorionic twin fetuses born late preterm. The early preterm group was divided into two according to whether they were admitted to the neonatal intensive care unit (NICU). The groups' cardiac function and Mod-MPI measurements were compared regarding their predictive ability for adverse perinatal outcomes. \u0000Results: The Mod-MPI values were similar between the early and late preterm groups (p=0.144). The left ventricular cardiac output Z-score was lower in the preterm group (p=0.014). The Mod-MPI and left ventricular outflow tract-isovolumetric contraction and isovolumetric relaxation times were significantly higher among the newborns admitted to the NICU in the early preterm group (p=0.002, p=0.003, and p=0.001, respectively). \u0000Conclusion: Our study suggests that the Mod-MPI measurement can be used to predict adverse perinatal outcomes in dichorionic twin fetuses born in the early preterm period.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"138 47","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141114664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Busra Demir Cendek, G. Dağdeviren, Ş. Çelen, A. Çağlar
Abstract Aim: Progesterone metabolites are known to be elevated in the serum of patients with intrahepatic cholestasis of pregnancy (ICP), and exogenous progesterone supplementation in early pregnancy may cause an increase in progesterone metabolites. The aim of this study is to investigate the relationship between ICP and exogenous progesterone intake. Materials and Methods: This study is a retrospective case-control study conducted between January 2015 and November 2023. The groups liver function tests, total bile acids, maternal age, body mass index, parity, history of cholestasis, history of progesterone use, gestational week in which pruritus symptoms occurred, gestational week, in which ICP was diagnosed, history of ursodeoxycholic acid intake, obstetric pathology, maternal comorbidities, week of delivery, delivery method, birth weight, APGAR scores were obtained from the database of our hospital and compared. Results: A total of 379 pregnant women including 79 with ICP and 300 control patients were included in the study. Nulliparity, history of cholestasis, and history of progesterone intake were significantly higher in the ICP group than in the control group. Conclusion: Intake of exogenous progesterone in early pregnancy may lead to ICP and have adverse effects on the fetus. Further studies are needed to investigate the role of progesterones in the development of ICP.
{"title":"Assessing the relationship between intrahepatic cholestasis of pregnancy and exogenous progesterone intake","authors":"Busra Demir Cendek, G. Dağdeviren, Ş. Çelen, A. Çağlar","doi":"10.38136/jgon.1410939","DOIUrl":"https://doi.org/10.38136/jgon.1410939","url":null,"abstract":"Abstract \u0000Aim: Progesterone metabolites are known to be elevated in the serum of patients with intrahepatic cholestasis of pregnancy (ICP), and exogenous progesterone supplementation in early pregnancy may cause an increase in progesterone metabolites. The aim of this study is to investigate the relationship between ICP and exogenous progesterone intake. \u0000Materials and Methods: This study is a retrospective case-control study conducted between January 2015 and November 2023. The groups liver function tests, total bile acids, maternal age, body mass index, parity, history of cholestasis, history of progesterone use, gestational week in which pruritus symptoms occurred, gestational week, in which ICP was diagnosed, history of ursodeoxycholic acid intake, obstetric pathology, maternal comorbidities, week of delivery, delivery method, birth weight, APGAR scores were obtained from the database of our hospital and compared. \u0000Results: A total of 379 pregnant women including 79 with ICP and 300 control patients were included in the study. Nulliparity, history of cholestasis, and history of progesterone intake were significantly higher in the ICP group than in the control group. \u0000Conclusion: Intake of exogenous progesterone in early pregnancy may lead to ICP and have adverse effects on the fetus. Further studies are needed to investigate the role of progesterones in the development of ICP.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"7 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141119704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amaç: İleri evre over malignitelerinde cerrahi sonrası morbidite nedenlerini, hastanede yatışla ilişkili risk faktörlerini değerlendirmek. Gereçler ve Yöntem: Eylül 2018–Aralık 2023 tarihleri arasında Mersin Üniversitesi Jinekolojik Onkoloji Bilim Dalı’na başvuran evre III over malignitesi tanısı olan 88 hasta çalışmaya dahil edildi. Hastaların demografik bilgileri, kanserin histolojik tipleri, tedavinin yönetimi ve sitoredüktif cerrahinin kapsamı, komplikasyonlar ve yönetimi, yoğun bakım ihtiyacı, morbidite ve erken dönem yatış süreleri, hastaneye yeniden kabuller ve müdahaleler değerlendirilmiştir. Bulgular: Primer sitoredüktif cerrahi (PSC) sonrası hastaların %70.6’sında, nüks sonrası cerrahilerin %74.1’inde, neoadjuvan kemoterapi sonrası interval sitoredüksiyon (NAKS-IS) yapılan hastaların %70.4’ünde komplet sitoredüksiyon sağlandı. Postoperatif erken dönemde morbiditenin en sık nedenleri sırası ile %17 yara yeri enfeksiyonu, %10.2 atelektazi, bulantı-ileus %9.1 idi. Yara yeri enfeksiyonu, atelektazi, ileus, tromboemboli görülme sıklığı açısından istatistiki olarak guruplar arası fark yoktu(p=0.537). Postoperatif dönemde yatış süresi ve 2. basamak yoğun bakım ihtiyacı açısından yönetimler arası fark yoktu(p>0.05). Postoperatif hospitalizasyonun en sık nedeni yara yeri enfeksiyonudur. Sonuç: Tedavi yönetimlerimiz arasında ve sitoredüksiyon başarıları açısından fark yoktu(p>0.05). NAKS-IS’in PSC’ye göre cerrahi süresi, yoğun bakım ihtiyacı, hastanede kalış süresi bakımından avantajlı bulunmuştur. Sitoredüksiyon oranları ve postoperatif komplikasyonlar açısından fark bulunmamıştır(p>0.05). Yara yeri enfeksiyonunun NAKS-IS te PSC’ye oranla fazla olma nedenini NAK bağlı sitopeni ile ilişkilendirebiliriz. PSC’de NAKS-IS’e kıyasla hızlı patoloji kullanımı, ameliyat süresi, postoperatif atelektazi ve ileus oranları artmıştır. Sitoredüktif cerrahi sonrası yara yeri enfeksiyonu, atelektazi, ileus ve tromboemboli açısından hastaların yakın takibi önemlidir.
{"title":"Evre III over malignitelerinde sitoredüktif cerrahi sonrası erken dönem morbiditenin değerlendirilmesi","authors":"Şevki Göksun Gökulu, Mürşide Çevikoğlu Kıllı, Ali Yıldızbakan, Görkem Ülger, Tolgay Tuyan İlhan","doi":"10.38136/jgon.1441216","DOIUrl":"https://doi.org/10.38136/jgon.1441216","url":null,"abstract":"Amaç: İleri evre over malignitelerinde cerrahi sonrası morbidite nedenlerini, hastanede yatışla ilişkili risk faktörlerini değerlendirmek. \u0000Gereçler ve Yöntem: Eylül 2018–Aralık 2023 tarihleri arasında Mersin Üniversitesi Jinekolojik Onkoloji Bilim Dalı’na başvuran evre III over malignitesi tanısı olan 88 hasta çalışmaya dahil edildi. Hastaların demografik bilgileri, kanserin histolojik tipleri, tedavinin yönetimi ve sitoredüktif cerrahinin kapsamı, komplikasyonlar ve yönetimi, yoğun bakım ihtiyacı, morbidite ve erken dönem yatış süreleri, hastaneye yeniden kabuller ve müdahaleler değerlendirilmiştir. \u0000Bulgular: Primer sitoredüktif cerrahi (PSC) sonrası hastaların %70.6’sında, nüks sonrası cerrahilerin %74.1’inde, neoadjuvan kemoterapi sonrası interval sitoredüksiyon (NAKS-IS) yapılan hastaların %70.4’ünde komplet sitoredüksiyon sağlandı. Postoperatif erken dönemde morbiditenin en sık nedenleri sırası ile %17 yara yeri enfeksiyonu, %10.2 atelektazi, bulantı-ileus %9.1 idi. Yara yeri enfeksiyonu, atelektazi, ileus, tromboemboli görülme sıklığı açısından istatistiki olarak guruplar arası fark yoktu(p=0.537). Postoperatif dönemde yatış süresi ve 2. basamak yoğun bakım ihtiyacı açısından yönetimler arası fark yoktu(p>0.05). Postoperatif hospitalizasyonun en sık nedeni yara yeri enfeksiyonudur. \u0000Sonuç: Tedavi yönetimlerimiz arasında ve sitoredüksiyon başarıları açısından fark yoktu(p>0.05). NAKS-IS’in PSC’ye göre cerrahi süresi, yoğun bakım ihtiyacı, hastanede kalış süresi bakımından avantajlı bulunmuştur. Sitoredüksiyon oranları ve postoperatif komplikasyonlar açısından fark bulunmamıştır(p>0.05). Yara yeri enfeksiyonunun NAKS-IS te PSC’ye oranla fazla olma nedenini NAK bağlı sitopeni ile ilişkilendirebiliriz. PSC’de NAKS-IS’e kıyasla hızlı patoloji kullanımı, ameliyat süresi, postoperatif atelektazi ve ileus oranları artmıştır. Sitoredüktif cerrahi sonrası yara yeri enfeksiyonu, atelektazi, ileus ve tromboemboli açısından hastaların yakın takibi önemlidir.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"110 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141124666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. A. Tokalioğlu, N. Sanlier, Gülşah Tiryaki Güner, Yeşim Özkaya Uçar, F. Kılıç, Hakan Raşit Yalçın, T. Turan
Aim: We aimed to analyses the high-risk HPV type distribution and pathology results in high-risk HPV positive patients. Materials and Methods: The research was retrospectively conducted and data was obtained from a tertiary gynecologic oncology colposcopy outpatient clinic. From September 2019 to December 2022, data from 3546 patients who tested positive for HPV and underwent colposcopic examination were analyzed. All patients granted the institution explicit permission to utilize their clinical data. Results: A total of 3546 patients with a median age of 40 years (range, 18–77 years) were analysed. Patient’s HPV status was; 1169 (33%) patients were HPV 16, 343 (9.7%) patients were HPV 18, and 2318 (65.4%) patients were HPV others. The detailed HPV positive results of patients were that 888 (25.4%) patients were only HPV 16, 197 (5.6%) patients were only HPV 18, and 2097 (59.9%) patients were only HPV others. In the study cohort, 529 (14.9%) patients had CIN 2+ lesions. HPV 16 and/or HPV 18 were detected in 331 (62.5%) of 529 patients with CIN 2+ lesions. The final pathology result of 507 (14.3%) patients was CIN 2/3 and of 22 (0.6%) patients was cancer. Conclusion: In conclusion, we found that while HPV other types were positive in two-thirds of the patients, HPV 16 and/or 18 were positive in more than four-fifths of the cancer cases. In the high-risk HPV positive patient group, HPV type can be used as a criterion when referring the patient to colposcopy
{"title":"HIGH-RISK HPV TYPES AND PATHOLOGY RESULTS IN PATIENTS WITH HIGH-RISK HPV POSITIVE","authors":"A. A. Tokalioğlu, N. Sanlier, Gülşah Tiryaki Güner, Yeşim Özkaya Uçar, F. Kılıç, Hakan Raşit Yalçın, T. Turan","doi":"10.38136/jgon.1454043","DOIUrl":"https://doi.org/10.38136/jgon.1454043","url":null,"abstract":"Aim: We aimed to analyses the high-risk HPV type distribution and pathology results in high-risk HPV positive patients. \u0000Materials and Methods: The research was retrospectively conducted and data was obtained from a tertiary gynecologic oncology colposcopy outpatient clinic. From September 2019 to December 2022, data from 3546 patients who tested positive for HPV and underwent colposcopic examination were analyzed. All patients granted the institution explicit permission to utilize their clinical data. \u0000Results: A total of 3546 patients with a median age of 40 years (range, 18–77 years) were analysed. Patient’s HPV status was; 1169 (33%) patients were HPV 16, 343 (9.7%) patients were HPV 18, and 2318 (65.4%) patients were HPV others. The detailed HPV positive results of patients were that 888 (25.4%) patients were only HPV 16, 197 (5.6%) patients were only HPV 18, and 2097 (59.9%) patients were only HPV others. In the study cohort, 529 (14.9%) patients had CIN 2+ lesions. HPV 16 and/or HPV 18 were detected in 331 (62.5%) of 529 patients with CIN 2+ lesions. The final pathology result of 507 (14.3%) patients was CIN 2/3 and of 22 (0.6%) patients was cancer. \u0000Conclusion: In conclusion, we found that while HPV other types were positive in two-thirds of the patients, HPV 16 and/or 18 were positive in more than four-fifths of the cancer cases. In the high-risk HPV positive patient group, HPV type can be used as a criterion when referring the patient to colposcopy","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"23 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141022551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Ulubaşoğlu, Meryem Kuru Pekcan, Gamze Yilmaz, G. Özakşit, Özlem Moraloğlu Tekin
Aim: The aim of this study is to investigate the effect of polycystic ovarian syndrome (PCOS) on obstetric and neonatal outcomes. Materials and Method: The:This study was conducted as a randomized controlled prospective at Ankara City Hospital obstetric clinic between 2020-2021.Total included a total of 200 pregnant women (18-45 years), of whom 101 had PCOS and 99 were healthy controls.Demographic characteristics of the groups were analyzed. The systolic blood pressure, diastoic blood pressure,insulin resistance , ovulation induction, insemination and newborn admission rates of the pregnant group were evaluated. Maternal age, fetal birth weight, gravidity, parity, BMI, gestational age, gestational age according to ultrasound, women height, weight, (BMI), weight gained during pregnancy, hemoglobin values were were compared between both groups. Results:In terms of the rates of ovulation induction, insemination, and admission to the neonatal unit for follow-up in pregnant women with PCOS were significant different found.Pregnant women with PCOS had higher rates of ovulation induction, insemination, and admission to the neonatal unit for follow-up.It was observed that cesarean section rates were higher in pregnant women with PCOS. Conclusion:It should be consıdered that pregnant pregnants wıth PCOS are more lıkely to have a cesarıan sectıon and theır newborn's are more lıkely to be admıtted to the newborn unıt for follow-up .This situation should be taken into consideration in the management of pregnant women.
{"title":"EFFECT ON OBSTETRIC RESULTS OF POLYCYSTIC OVARY SYNDROME","authors":"H. Ulubaşoğlu, Meryem Kuru Pekcan, Gamze Yilmaz, G. Özakşit, Özlem Moraloğlu Tekin","doi":"10.38136/jgon.1447264","DOIUrl":"https://doi.org/10.38136/jgon.1447264","url":null,"abstract":"Aim: The aim of this study is to investigate the effect of polycystic ovarian syndrome (PCOS) on obstetric and neonatal outcomes. \u0000Materials and Method: The:This study was conducted as a randomized controlled prospective at Ankara City Hospital obstetric clinic between 2020-2021.Total included a total of 200 pregnant women (18-45 years), of whom 101 had PCOS and 99 were healthy controls.Demographic characteristics of the groups were analyzed. The systolic blood pressure, diastoic blood pressure,insulin resistance , ovulation induction, insemination and newborn admission rates of the pregnant group were evaluated. Maternal age, fetal birth weight, gravidity, parity, BMI, gestational age, gestational age according to ultrasound, women height, weight, (BMI), weight gained during pregnancy, hemoglobin values were were compared between both groups. \u0000Results:In terms of the rates of ovulation induction, insemination, and admission to the neonatal unit for follow-up in pregnant women with PCOS were significant different found.Pregnant women with PCOS had higher rates of ovulation induction, insemination, and admission to the neonatal unit for follow-up.It was observed that cesarean section rates were higher in pregnant women with PCOS. \u0000Conclusion:It should be consıdered that pregnant pregnants wıth PCOS are more lıkely to have a cesarıan sectıon and theır newborn's are more lıkely to be admıtted to the newborn unıt for follow-up .This situation should be taken into consideration in the management of pregnant women.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":" 45","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141129887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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