MORBIDITY PATTERN OF SMALL FOR GESTATIONAL AGE BABIES ADMITTED IN A NEONATAL CARE UNIT

B. Kalakheti, A. Lamichhane, Bikesh Prajapati, H. Upadhyay
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Abstract

Background: The neonatal period of the small for gestational age (SGA) neonates is the most vulnerable phase; the neonatal morbid conditions along with the mortality being the major health issues in the developing countries like Nepal. The objective of this study was to assess the morbidity pattern of the SGA neonates admitted in the neonatal intensive care unit. Methods: A hospital base cross-sectional study was carried out in 100 SGA neonates admitted in the neonatal care unit of College of Medical Sciences Teaching Hospital, Bharatpur, Nepal from May 2020 to April 2021 Small for gestational age neonates (SGA) was defined as birth weight <10th percentile for gestational age by Lubchenco’s growth chart. Infant characteristics and neonatal outcomes were assessed during the hospital stay and the data was entered in the SPSS v23.0.  Results: Among the total 100 cases of SGA neonates, 66 % were male. The mean birth weight was 1900 ±SD 381gm (range 1000-2500 gm). Term SGA neonates accounted for 60% while preterm SGA neonates were 40%. Common morbidities seen in SGA neonates were sepsis (44%), hyperbilirubinemia (34%), perinatal depression/birth asphyxia (34%) and shock (22%). While comparing the morbidities between term and preterm neonates, a significant correlation was observed between hypothermia (p-value = 0.001), polycythemia (p-value = 0.001), NEC (p-value= 0.004) and perinatal depression/asphyxia (0.013) with the period of gestation. Mortality was observed in 8% due to various perinatal problems.  Conclusions: From this study, we can conclude that SGA is associated with various morbidities, sepsis being the most common morbidity amongst perinatal asphyxia, hyperbilirubinemia, hypothermia and hypoglycemia.
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在新生儿护理病房的小胎龄婴儿的发病率模式
背景:小胎龄儿(SGA)的新生儿期是最脆弱的阶段;新生儿疾病和死亡率是尼泊尔等发展中国家的主要健康问题。本研究的目的是评估新生儿重症监护病房收治的SGA新生儿的发病率模式。方法:对2020年5月至2021年4月在尼泊尔巴拉特普尔医学学院教学医院新生儿护理部收治的100例SGA新生儿进行医院基础横断面研究。根据Lubchenco生长图,小于胎龄新生儿(SGA)定义为出生体重<胎龄第10百分位。在住院期间评估婴儿特征和新生儿结局,并将数据输入SPSS v23.0。结果:100例SGA新生儿中,男性占66%。平均出生体重为1900±SD 381gm(范围1000-2500 gm)。足月SGA新生儿占60%,早产儿SGA新生儿占40%。SGA新生儿常见的发病率是败血症(44%)、高胆红素血症(34%)、围产期抑郁/出生窒息(34%)和休克(22%)。在比较足月新生儿和早产儿的发病率时,发现低温症(p值= 0.001)、红细胞增多症(p值= 0.001)、NEC (p值= 0.004)和围产期抑郁/窒息(p值= 0.013)与妊娠期有显著相关性。由于各种围产期问题,死亡率为8%。结论:从本研究中,我们可以得出SGA与多种发病率相关,脓毒症是围产期窒息、高胆红素血症、低体温和低血糖中最常见的发病率。
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