Modern problems of reproductive and respiratory syndrome of pigs (RRSS) vaccine prevention

A. Gusev, S. Engashev, V. A. Babak
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Abstract

To date, the swine reproductive and respiratory syndrome virus (RRSS) has been registered in most countries of the world, including Russia. This disease remains one of the important problems in pig breeding, as it causes huge losses to this industry.The authors conducted a study where epizootological data and clinical signs of the incidence of RRSS in the conditions of the breeding farm "Zadneprovsky" and materials for evaluating the effectiveness of RRSS vaccine prevention with an analysis of economic indicators. The diagnosis of RRSS was made on the basis of clinical, pathoanatomic and serological research methods. By the number of antibodies in the blood serum of animals, the intensity of immunity to the RRSS virus was judged. Virus-specific antibodies were determined by enzyme immunoassay (ELISA).It is established that if the virus appears in the herd for the first time, all sows with impaired reproductive function, accompanied by 100% abortions, premature birth, become ill. Among the piglets born from sick sows, there are a large number of stillbirths, and among the surviving piglets, there is a high mortality rate, stunting and unsuitability for cultivation. It is noted that the number of stillborn piglets is always higher in the first moments of the onset of the disease than with repeated farrowing.After getting over the disease, the bulk of sows quickly recover and, with repeated farrowing, bring viable piglets. Immunization of piglets against the background of a decrease in maternal immunity with a live vaccine against RRSS is accompanied by the formation of a tense immunity that protects them from the disease.Currently, in many pig farms, vaccination of pigs against RRSS is included in the mandatory program of preventive vaccinations against infectious diseases.
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猪繁殖与呼吸综合征(RRSS)疫苗预防的现代问题
迄今为止,猪繁殖与呼吸综合征病毒(RRSS)已在世界上大多数国家登记,包括俄罗斯。这种疾病仍然是养猪业的重要问题之一,因为它给养猪业造成了巨大的损失。作者对“Zadneprovsky”养殖场条件下RRSS发病率的流行病学数据和临床症状进行了研究,并对经济指标进行了分析,以评估RRSS疫苗预防效果。RRSS的诊断是在临床、病理和血清学研究方法的基础上做出的。通过测定动物血清中抗体的数量,判断动物对RRSS病毒的免疫强度。采用酶免疫分析法(ELISA)检测病毒特异性抗体。可以确定的是,如果该病毒首次出现在猪群中,所有生殖功能受损的母猪都会患病,并伴有100%的流产和早产。病母猪产的仔猪中存在大量死产,存活仔猪中存在死亡率高、发育迟缓、不适宜养殖等问题。值得注意的是,死产仔猪的数量在发病的最初时刻总是高于重复分娩。在克服疾病后,大部分母猪迅速恢复,并通过反复分娩,带来可存活的仔猪。在母体免疫力下降的背景下,用RRSS活疫苗对仔猪进行免疫,同时形成一种保护仔猪免受疾病侵害的紧张免疫。目前,在许多养猪场,猪的RRSS疫苗接种被列入强制性预防传染病疫苗接种计划。
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