Recent Advances in Injectable Hydrogels for Biomedical Applications

Eko Adi Prasetyanto
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引用次数: 2

Abstract

Injectable hydrogels, a class of hydrogel, have received a lot of attention in biomedical applications due to its versatility. It is reported that injectable hydrogel can be applied in various biomedical procedures for example as submucosal fluid cushion, periodontal implant, and cartilage and bone tissue engineering. In addition to its easy delivery (implantation), this class of hydrogel can be tailored to match specific applications. The customization of this hydrogel can be easily executed by changing polymeric backbone of hydrogel, choosing different types of crosslinking or by adding nanoparticles to form hybrid hydrogel systems. Physical properties, compatibility and biodegradability of the resulted materials are important factors for designing injectable hydrogels. In this Recent Research Progress, we highlight the state-of-the-art injectable hydrogels and note the general requirements of an ideal injectable hydrogel for biomedical applications.
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生物医学注射用水凝胶研究进展
注射型水凝胶作为水凝胶的一类,由于其多功能性在生物医学领域的应用受到了广泛的关注。据报道,可注射水凝胶可应用于各种生物医学程序,如粘膜下液垫、牙周种植、软骨和骨组织工程。除了易于输送(植入)外,这类水凝胶还可以根据具体应用进行定制。通过改变水凝胶的聚合主链,选择不同类型的交联或添加纳米颗粒形成混合水凝胶体系,可以很容易地实现这种水凝胶的定制。制备材料的物理性能、相容性和生物降解性是设计可注射水凝胶的重要因素。在最近的研究进展中,我们强调了最先进的可注射水凝胶,并指出了生物医学应用中理想的可注射水凝胶的一般要求。
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