Synthesis and characterization of ZnO nanostructures with antimicrobial properties

D. Yiamsawas, K. Boonpavanitchakul, W. Kangwansupamonkon
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引用次数: 2

Abstract

ZnO nano-structures were synthesized via solvothermal processes in the presence of polymer template at 80degC for 24 hours and characterized by X-ray Diffraction (XRD), UV-vis spectroscopy, and Transmission Electron Microscopy (TEM) combined with energy dispersive X-ray spectroscopy (EDX) for elemental mapping. The effects of molecular weight of poly(vinyl pyrrolidone) (PVP) and poly(ethylene glycol) (PEG) on the morphology and size of ZnO were determined. The typical width and length are in the range of 9-12 nm and 58-97 nm, respectively. The ZnO nanocrystal showed antibacterial activity against Staphylococus aureus, Escherichia coli and Micrococcus luteus, which minimum inhibition concentration at 90% (MIC 90) is 156 mug/ml, 1.25 mg/ml and 20-40 mug/ml, respectively for PEG 6000 and 313 mug/ml, 2.5 mg/ml and 20-40 mug/ml, respectively for PVP 30K.
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抗菌氧化锌纳米结构的合成与表征
在聚合物模板存在下,采用溶剂热法在80℃下合成ZnO纳米结构,并通过x射线衍射(XRD)、紫外可见光谱(UV-vis)和透射电子显微镜(TEM)结合能量色散x射线能谱(EDX)进行元素图谱表征。研究了聚乙烯基吡咯烷酮(PVP)和聚乙二醇(PEG)的分子量对ZnO形貌和尺寸的影响。典型的宽度和长度分别在9 ~ 12 nm和58 ~ 97 nm之间。氧化锌纳米晶对金黄色葡萄球菌、大肠杆菌和黄体微球菌具有抑菌活性,对PEG 6000和PVP 30K的最小抑制浓度(MIC 90)分别为156 mg/ml、1.25 mg/ml和20 ~ 40 mg/ml,对PVP 30K的最小抑制浓度(MIC 90)分别为2.5 mg/ml和20 ~ 40 mg/ml。
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