MANAGEMENT OF BILHARZIASIS OF THE CONUS MEDULLARIS

K. Kenawy, A. Kasim, Nahla Mahmoud, Mahmoud Saif-Al-Islam, Khalid Naser
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Abstract

Schistosomiasis is one of the most prevalent tropical diseases in the world. Spinal cord neuroschistosomiasis is an uncommon complication mainly due to infestation by Schistosoma mansoni and may be caused by Schistosoma haematobium. Diagnosis depends on detection of anti-bilharzial antibodies and MRI of lumbar spine. The main treatment is medical. Surgery is an option for resistant cases. From January 2009 to January 2020, we reviewed patients with conus medullaris bilharziasis, who received different modalities of management. Clinical presentation, treatment plans, outcomes, and complications were reported. We studied 21 patients with conus bilharziasis. Males constituted 95.2 % and the age ranged from 8-12 years with a mean of 9.8 years. Low back pain and hypothesia were present in 100 % of patients while retention of urine in 95.2%. Examination of urine for S. haematobium ova was negative in 100 %, while stool examination for S. mansoni ova was positive in 4.8%. Mild to moderate expansion of the distal spinal cord and conus medullaris was seen in 100 % of MR images. After medical treatment; complete improvement was achieved in 71.4%, and partial improvement in 9.5%. Surgery was done in 19 % after failure of medical treatment and physiotherapy of whom, 4.8 % improved completely, 4.8 % improved partially while no improvement occurred in 9.5%. Conus lesions in endemic areas should trigger the possibility of Bilharziasis. Early diagnosis by MRI and positive antibilharzial antibodies is essential for management to avoid complications.
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髓圆锥血吸虫病的治疗
血吸虫病是世界上最流行的热带病之一。脊髓神经血吸虫病是一种罕见的并发症,主要由曼氏血吸虫感染引起,也可能由血血吸虫引起。诊断依赖于腰椎的抗bilharial抗体检测和MRI。主要的治疗方法是药物治疗。对于耐药性病例,手术是一种选择。从2009年1月至2020年1月,我们回顾了接受不同治疗方式的髓锥血吸虫病患者。报告临床表现、治疗方案、结局及并发症。我们研究了21例圆锥血吸虫病。男性占95.2%,年龄8 ~ 12岁,平均9.8岁。100%的患者出现腰痛和感觉减退,95.2%的患者出现尿潴留。尿检血链球菌卵阴性率为100%,粪便检曼氏链球菌卵阳性率为4.8%。轻度至中度的远端脊髓和髓圆锥扩张在100%的MR图像中可见。经医疗后;完全改善的占71.4%,部分改善的占9.5%。药物治疗和物理治疗失败后行手术治疗的占19%,其中完全好转的占4.8%,部分好转的占4.8%,无好转的占9.5%。流行地区的圆锥病变应引发血吸虫病的可能性。早期的MRI诊断和抗双胞抗体阳性对于避免并发症的处理至关重要。
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