GENETIC INVOLVEMENT IN DENTAL TREATMENT FEAR

Donja Khodabakhshi, C. Piña, A. Teles, I. Cardoso
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Abstract

Being a global health concern, dental fear and anxiety is estimated to affect at least one in ten individuals all around the globe. Ensuing the vicious circle of dental fear comes detrimental outcomes in quality of life. Despite the wide range of knowledge concerning the environmental factors that contribute to the acquisition of dental fear and anxiety, the prevalence has not decreased, giving researchers the possibility to highlight other concomitant etiological factors. The possible hereditary or genetic component is most recently being explored, although facing tremendous dynamical elements to substantially delineate its role. The purpose of this review was to explore, reflect and call attention to the current knowledge of the genetic involvement of dental treatment fear and anxiety. Although findings mostly stress the relation between dental fear to other phenotypes giving rise to individual vulnerability, there are studies disclosing suggestive heritability rates for dental fear and anxiety.
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牙科治疗恐惧的基因参与
牙科恐惧和焦虑是一个全球健康问题,据估计,全球至少有十分之一的人受到牙科恐惧和焦虑的影响。随之而来的是牙医恐惧的恶性循环,对生活质量产生了有害的影响。尽管人们对环境因素对牙科恐惧和焦虑的产生有广泛的了解,但患病率并没有下降,这给了研究人员强调其他伴随病因的可能性。最近正在探索可能的遗传或遗传成分,尽管面临着大量的动力学因素来实质性地描述其作用。本综述的目的是探索、反思和呼吁关注目前关于牙科治疗恐惧和焦虑的遗传参与的知识。尽管研究结果大多强调牙科恐惧与其他导致个体脆弱性的表型之间的关系,但也有研究揭示了牙科恐惧和焦虑的暗示性遗传率。
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