The Effects of Essential Oil and Massage on Patients’ Affected by Alzheimer’s Disease. An Observational Study

Antonio Bonacaro, Ivan Rubbi, Carmela Triglia, Valeria Cremonini, A. Conti, S. Brownie
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Abstract

Background: Alzheimer's Disease (AD) is the most widespread form of dementia. The present study analyses the effects of aromatherapy using Melissa Officinalis essential oil, applied by massage to the hands and forearms of patients suffering from Alzheimer's disease. and to evaluate the effect on their perceived overall quality of life. Methods: A prospective observational study was conducted in two nursing homes in Italy in 2018. Data were collected through individual qualitative structured interviews based on the Quality of Life in Alzheimer’s Disease (QoL-AD) questionnaire and the Mini Mental State Examination (MMSE). The authors referred to STROBE guidelines for quality reporting of observational studies. Results: Treatment with Melissa Officinalis showed positive effects on all patients after the 12th week of treatment. The results were most evident in patients in class 3 MMSE. However, class 4 MMSE patients also benefited from the treatment. Conclusions: The aromatherapy treatment delivered in this observational study, using Melissa Officinalis essential oil applied to hands and forearms, showed an improvement in the quality of life of the patients living in two different nursing homes. Due to the small sample size in this study, it is suggested that more research be done on the effects and effectiveness of aromatherapy with Melissa Officinalis essential oil for Alzheimer's disease patients.
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精油和按摩对老年痴呆症患者的影响。观察性研究
背景:阿尔茨海默病(AD)是最常见的痴呆形式。本研究分析了使用Melissa Officinalis精油的芳香疗法的效果,通过按摩阿尔茨海默病患者的手和前臂。并评估对他们整体生活质量的影响。方法:2018年在意大利的两家养老院进行前瞻性观察研究。通过基于阿尔茨海默病生活质量(QoL-AD)问卷和迷你精神状态检查(MMSE)的个体定性结构化访谈收集数据。作者参考了STROBE观察性研究质量报告指南。结果:经12周治疗后,所有患者均有良好的治疗效果。结果在3级MMSE患者中最为明显。然而,4级MMSE患者也从治疗中获益。结论:在这项观察性研究中,将Melissa Officinalis精油应用于手部和前臂的芳香疗法,改善了住在两家不同疗养院的患者的生活质量。由于本研究样本量较小,建议进一步研究梅丽莎精油芳香疗法对阿尔茨海默病患者的疗效。
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