Treatment of Primary Pulmonary Carcinoma with Traditional Chinese Veterinary Medicine After Conventional Therapy Failure

Lorrie Hale-Mitchell
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Abstract

A 10-year-old castrated male German Shorthaired Pointer was referred to a tertiary veterinary teaching hospital (VTH) with a 4-month history of anorexia, hindlimb weakness and occasional coughing. The coughing was minimally responsive to various antibiotic/steroid combinations prior to thoracic radiographs identifying pulmonary masses. Diagnostic workup and imaging by the VTH oncology service confirmed 2 pulmonary masses, 4.8×3.7 cm and 1.4×1.6 cm, in the left and right middle lung lobes, respectively. Fine needle aspirate diagnosis was primary mucinous bronchoalveolar carcinoma. With masses in two lobes, the condition was not amendable to surgery, therefore, chemotherapy was suggested along with traditional Chinese veterinary medicine (TCVM) therapy to improve quality of life. Initial TCVM Patterns were Spleen Qi Deficiency, Kidney Qi Deficiency and Lung Blood Stasis. Therapy was designed to stimulate the dog’s appetite, counter chemotherapy negative side-effects and strengthen the hindlimbs. Acupuncture, Tui-na, and Chinese herbal medicines (CHM) were initially started along with chemotherapeutics. The Tui-na and CHM treatments quickly became the main therapy when the dog was unable to tolerate chemotherapeutics or acupuncture. Survival was expected to be 6-9 months with chemotherapeutics or 2-5 months without. Using TCVM therapies, the dog survived 19 months after diagnosis, with an excellent quality of life. This case demonstrates the potential benefits of combining traditional Chinese veterinary medicine with conventional therapy for oncology patients to extend survivability while improving quality of life. Optimal TCVM treatment should be based on adjusting treatment plans guided by the changing TCVM Pattern(s) presented by a patient at each clinical exam.
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中药治疗原发性肺癌常规治疗失败后的疗效观察
一只10岁阉割的雄性德国短毛猎犬因4个月的厌食症、后肢无力和偶尔咳嗽被转至三级兽医教学医院。在胸部x线片确定肺部肿块之前,咳嗽对各种抗生素/类固醇组合的反应最小。VTH肿瘤诊断及影像学证实肺肿块2个,分别为4.8×3.7 cm和1.4×1.6 cm,位于左、右肺中叶。细针抽吸诊断为原发性黏液支气管肺泡癌。双叶肿物不宜手术治疗,建议化疗配合中药治疗,以提高生活质量。TCVM初始证型为脾虚、肾虚、肺血瘀。治疗的目的是刺激狗的食欲,对抗化疗的负面副作用,并加强后肢。针灸、推拿和中草药(CHM)最初是与化疗一起开始的。当狗不能忍受化疗或针灸时,推拿和中医治疗迅速成为主要的治疗方法。化疗组生存期为6-9个月,未化疗组生存期为2-5个月。使用TCVM治疗,狗在诊断后存活了19个月,生活质量很好。该病例表明,将传统兽药与常规治疗相结合,对肿瘤患者在提高生活质量的同时延长生存期的潜在益处。最佳的TCVM治疗应以每次临床检查中患者呈现的TCVM模式的变化为指导,调整治疗方案。
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