Chapter 1. Introduction to Proteome Informatics

C. Bessant
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Abstract

At its core, proteomics can be defined as the branch of analytical science concerned with identifying and, ideally, quantifying every protein within a complex biological sample. This chapter provides a high level overview of this field and the key technologies that underpin it, as a primer for the chapters that follow. It also introduces the field of proteome informatics, and explains why it is an integral part of any proteomics experiment.
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第1章。蛋白质组信息学导论
在其核心,蛋白质组学可以被定义为分析科学的一个分支,涉及识别和理想情况下,定量复杂生物样品中的每种蛋白质。本章提供了该领域的高层次概述和支撑它的关键技术,作为后续章节的入门。它还介绍了蛋白质组信息学领域,并解释了为什么它是任何蛋白质组学实验的组成部分。
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Chapter 8. MS2-Based Quantitation Chapter 10. Data Analysis for Data Independent Acquisition Chapter 16. Proteomics Informed by Transcriptomics Chapter 3. Peptide Spectrum Matching via Database Search and Spectral Library Search Chapter 1. Introduction to Proteome Informatics
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