Multi-modal neural microprobe integrating silicon microelectrodes and polymeric microchannels

Abstract

Direct interfacing with brain tissues for neuroscience, neural prosthetics, and local treatment of brain diseases necessitates the implantation of arrays of electrodes to stimulate, record electrical activity, and deliver drugs to specific locations in the brain. Here, we present novel elongated multi-modal neural microprobe capable of simultaneously recording the electrical activity of the brain and delivering drugs to the diagnosed location through polymeric microchannel embedded on top of the electrode. The functionality of the electrical part of the microprobe was tested in rats and high frequency spikes were recorded.