NEUROLOGICAL ADVERSE EVENTS FOLLOWING IMMUNIZATION (AEFI) ON HEALTH WORKFORCE OF A SECONDARY REFERRAL HOSPITAL IN SOUTH SULAWESI WHO RECEIVED THE

Lutpyah L, Arthur Hendrik Philips Mawuntu, Hamdana H, Mieke Actrees Hanna Nelly Kembuan
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Abstract

Background: The COVID-19 vaccination can relate to the occurrence of neurological adverse events following immunization (AEFI) that could impact work and daily activities. This problem is particularly important in the health workforce. However, little is known about neurological AEFI among the health workforce working in peripheral facilities. Objective: To study the neurological AEFIs and their impact among the health workforce who received the COVID-19 vaccination in a secondary referral hospital in South Sulawesi, the Andi Makassau Hospital (Rumah Sakit Umum Daerah Andi Makassau/RSAM). Methods: The COVID-19 pandemic, we created a questionnaire about neurological AEFIs and their effects which were distributed online using the Google Form application to the health workforce at the RSAM who had received at least one dose of COVID-19 vaccination. Results: We obtained 97 subjects. There were 78.5% neurological AEFIs with the most reported type being muscle pain (16%). Most neurological AEFIs were experienced by women (84.9%), age group 21-35 years (53.8%), and non-doctors/nurses (60.8%). The significant influencing factors in multivariate analysis were age group 36-45 years (p = 0.04), nursing proffesion (p = 0.005), and non- viral-based baccine type (p = < 0.0001). Conclusion: Neurological AEFI is commonly found among the health workforce who received the COVID-19 vaccination. However, it only has a little impact on their work and attitudes towards vaccination. This may be because all subjects experienced mild neurological AEFI.
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南苏拉威西一家二级转诊医院卫生工作人员接种疫苗后神经系统不良事件(aefi)
背景:COVID-19疫苗接种可能与免疫后神经系统不良事件(AEFI)的发生有关,可能影响工作和日常活动。这一问题在卫生人力中尤为重要。然而,在外围设施工作的卫生工作者中,对神经系统急性脑损伤知之甚少。目的:研究南苏拉威西省二级转诊医院Andi Makassau医院(Rumah Sakit Umum Daerah Andi Makassau/RSAM)接受COVID-19疫苗接种的卫生工作者的神经系统不良反应及其影响。方法:在COVID-19大流行期间,我们制作了一份关于神经系统AEFIs及其效果的调查问卷,并使用Google Form应用程序在线分发给至少接种过一剂COVID-19疫苗的RSAM卫生工作者。结果:共纳入97例受试者。78.5%为神经性急性脑损伤,其中肌肉疼痛类型最多(16%)。大多数神经系统急性脑损伤患者为女性(84.9%)、21-35岁年龄组(53.8%)和非医生/护士(60.8%)。多因素分析的显著影响因素为年龄36 ~ 45岁(p = 0.04)、护理专业(p = 0.005)、非病毒型疫苗(p = < 0.0001)。结论:神经性急性脑损伤常见于接种COVID-19疫苗的卫生工作者。然而,这对他们的工作和对疫苗接种的态度只有很小的影响。这可能是因为所有受试者都经历了轻度神经性急性脑损伤。
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