Probing and using the dielectric properties of microtubules within microsystems integrating Indium-Tin oxide microelectrodes

Abstract

The present paper describes the use of indium-tin oxide microelectrodes for manipulating microtubules in solution through interaction with electric fields. The experimental set-up that is described here is a platform for both investigating the fundamental dielectric properties of microtubules and developing methods to exert control over their behaviour in solution. Direct applications of such methods can be found in the development of microsystems integrating nano-machines based on motor proteins such as kinesin or dynein. Electro-rotation of microtubules in solution is presented as an example of interaction between microtubules and electric field