{"title":"Quantitative relations between acoustic inertial cavitation and gene transfection rate/cell viability","authors":"Chun-Yen Lai, Chia-Hsuan Wu, C. Chen, Pai-Chi Li","doi":"10.1109/ULTSYM.2005.1603197","DOIUrl":null,"url":null,"abstract":"Ultrasound has been utilized to assist gene transfection. In combination with ultrasound, microbubble-based contrast agents have also been used to enhance the transfection efficiency by inducing acoustic inertial cavitation. However, the relations between inertial cavitation and gene transfection rate/cell viability are still unknown. It is the primary purpose of this study to examine the relations experimentally and quantitatively. A commercial contrast agent Levovist ® was used, and","PeriodicalId":302030,"journal":{"name":"IEEE Ultrasonics Symposium, 2005.","volume":"46 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Ultrasonics Symposium, 2005.","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ULTSYM.2005.1603197","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Ultrasound has been utilized to assist gene transfection. In combination with ultrasound, microbubble-based contrast agents have also been used to enhance the transfection efficiency by inducing acoustic inertial cavitation. However, the relations between inertial cavitation and gene transfection rate/cell viability are still unknown. It is the primary purpose of this study to examine the relations experimentally and quantitatively. A commercial contrast agent Levovist ® was used, and