Head and Neck Lymphomas in Jos University Teaching Hospital Nigeria: A Five Year Review

Nimkur Lohpon Tonga, Obebe Francis Ameh, Okoye Chukwuma, J. Emmanuel
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Abstract

: Introduction : Lymphomas are heterogeneous group of lymphoid tissues traditionally categorized as either Hodgkin’s Lymphoma (HL) or Non-Hodgkin’s Lymphoma (NHL). The head and neck region is rich in lymphoid tissues, thus a fertile anatomic site for the development of lymphoid proliferative diseases like lymphomas. In the head and neck, malignant lymphomas account for 5% of all malignant neoplasm; Non-Hodgkin’s Lymphoma (NHL) is the most common accounting for 75%. The clinical behaviour and manifestations of Lymphomas in the head and neck lack specific characteristics that would enable attribution to a specific lymphoma entity without biopsy and histological evidence. Materials and Methods : It is a 5 year retrospective study of confirmed histopathological analysis of head and neck lymphomas from 1 st January 2017 to31 st December 2021. Case notes of all histopathologically confirmed head and neck lymphomas were retrieved from the medical records department and also theatre records as supportive data were analysed for age, sex, histological diagnosis, tumour site, duration of symptoms before presentation and treatment modality; and then discussed. Results :- The total number of patients seen during the period under review was 1678, 16 patients had histopathologically confirmed lymphomas out of 388 patients with head and neck tumours, thus prevalence of 0.1% and 4.1% of all head and neck tumours. Male to Female ratio of 5:1, age range of 4 to 62 years, mean age of 29 years. Most common tumour site is the cervical region-315; the most frequently seen histological type is the Non Hodgkin’s lymphoma (NHL) and the most common duration of symptom before presentation is over 1 year-50%. All patients had chemotherapy as a treatment modality. Conclusion : This study reveals the management challenges of the head and neck lymphomas are due to late presentation, financial constraints and ignorance. Health awareness and adequate Health Insurance Policy are needed to cope or mitigate these problems.
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尼日利亚乔斯大学教学医院头颈部淋巴瘤:五年回顾
淋巴瘤是一种异质性淋巴组织,传统上分为霍奇金淋巴瘤(HL)和非霍奇金淋巴瘤(NHL)。头颈部是淋巴组织丰富的区域,是淋巴瘤等淋巴细胞增生性疾病发生的肥沃解剖部位。在头颈部,恶性淋巴瘤占所有恶性肿瘤的5%;非霍奇金淋巴瘤(NHL)是最常见的,占75%。头颈部淋巴瘤的临床行为和表现缺乏特异性特征,无法在没有活检和组织学证据的情况下将其归因于特定的淋巴瘤实体。材料和方法:这是一项为期5年的回顾性研究,对2017年1月1日至2021年12月31日头颈部淋巴瘤的组织病理学分析进行了证实。从医疗记录部门检索了所有经组织病理学证实的头颈部淋巴瘤的病例记录,并分析了作为支持性数据的手术室记录,包括年龄、性别、组织学诊断、肿瘤部位、症状出现前持续时间和治疗方式;然后讨论。结果:-在回顾期间所见的患者总数为1678例,388例头颈部肿瘤患者中有16例经组织病理学证实为淋巴瘤,患病率为0.1%和4.1%头颈部肿瘤。男女比例为5:1,年龄范围4 ~ 62岁,平均年龄29岁。最常见的肿瘤部位是宫颈-315;最常见的组织学类型是非霍奇金淋巴瘤(NHL),最常见的症状出现前持续时间超过1年-50%。所有患者均以化疗作为治疗方式。结论:本研究揭示了头颈部淋巴瘤的管理挑战是由于迟到,经济限制和无知。需要健康意识和适当的健康保险政策来应付或减轻这些问题。
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