MORE ON THE GLOBAL BURDEN OF SHIGELLOSIS

D. Cohen
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Abstract

The article “Shigellosis outbreaks-an update” by Gabriela Loredana Popa and Mircea Ioan Popa provides an overview of recent shigellosis outbreaks worldwide after scrutinizing ProMed communications of the last years [1]. A special review section is dedicated to Shigella spp. associated outbreaks in the European region. As background, the authors reiterate the clinical and epidemiological characteristics of the disease. The paper highlights the continuing burden of shigellosis worldwide including the rise of antibiotic-resistant Shigella isolates and the emerging epidemic transmission of multi-drug resistant Shigella spp. among MSM communities. The authors recommend that shigellosis should not be neglected in the global efforts to prevent and control infectious diseases of public health importance. The comments below reinforce the message of this review with additional evidence from recent studies on the importance of Shigella as the leading cause of moderate to severe diarrhea (MSD) and dysentery globally and on the urgent need for licensed vaccines to reduce the burden of shigellosis primarily in children under 5 years of age in lowand-middle-income-countries (LMICs).
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更多关于志贺氏菌病的全球负担
Gabriela Loredana Popa和Mircea Ioan Popa撰写的文章“志贺氏菌病暴发——最新情况”在审查了过去几年的ProMed传播后,概述了最近世界范围内的志贺氏菌病暴发[1]。一个特别审查章节专门讨论欧洲区域与志贺氏菌相关的疫情。作为背景,作者重申了该病的临床和流行病学特征。该论文强调了志贺氏菌病在世界范围内的持续负担,包括耐抗生素志贺氏菌分离株的增加和多重耐药志贺氏菌在男男性接触者社区中的流行传播。这组作者建议,在全球预防和控制具有公共卫生重要性的传染病的努力中不应忽视志贺氏菌病。以下评论通过来自近期研究的更多证据加强了本综述的信息,这些研究表明志贺氏菌是全球中度至重度腹泻(MSD)和痢疾的主要原因,迫切需要获得许可的疫苗,以减轻志贺氏菌病的负担,主要是在中低收入国家(LMICs)的5岁以下儿童中。
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