Effect of gelatin concentration on pores and swelling behaviour of a composite bone scaffold

Abstract

composites have a wide range of applications in biomedical engineering as drug delivery templates and cell scaffolds. In this study, a composite scaffold of Chitosan-Gelatin-TCP was fabricated through freeze drying method and effect of gelatin concentration on porosity and swelling of scaffolds was investigated. Morphology and porosity of scaffolds was assessed by SEM. Binding of elements in composite was shown by FTIR and swelling test was performed in PBS. The results showed there exist a direct relationship between amount of gelatin in scaffold, pore size, porosity, and swelling ratio.