SMC Difference of Normal and Cancerous Human Urothelial Cells Quantified with an Opto-Electrokinetic Device

Ya-Lan Lin, Na Liu, Yang Yang, Shaorong Xie, Liang Dong, Yan Peng, Huayan Pu, P. Chiou, W. J. Li, Yu Sun
{"title":"SMC Difference of Normal and Cancerous Human Urothelial Cells Quantified with an Opto-Electrokinetic Device","authors":"Ya-Lan Lin, Na Liu, Yang Yang, Shaorong Xie, Liang Dong, Yan Peng, Huayan Pu, P. Chiou, W. J. Li, Yu Sun","doi":"10.1109/MARSS.2018.8481192","DOIUrl":null,"url":null,"abstract":"This paper reports the use of an opto-electrokinetic (OEK) device to measure the specific membrane capacitance (SMC) of malignant human bladder cancer cells (RT4) and benign human urothelial cells (SV-HUV-l). Experimental results, for the first time, show that RT4 cells (n=54) have a significantly larger SMC than SV-HUV-l cells (n=48), 15.8 ± 3.5 mF/m2vs. 12.5 ± 2.3 mF/m2, indicating that SMC could be a potentially useful biomarker for distinguishing malignant and benign human urothelial cells to aid bladder cancer detection.","PeriodicalId":118389,"journal":{"name":"2018 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS)","volume":"40 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2018 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/MARSS.2018.8481192","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2

Abstract

This paper reports the use of an opto-electrokinetic (OEK) device to measure the specific membrane capacitance (SMC) of malignant human bladder cancer cells (RT4) and benign human urothelial cells (SV-HUV-l). Experimental results, for the first time, show that RT4 cells (n=54) have a significantly larger SMC than SV-HUV-l cells (n=48), 15.8 ± 3.5 mF/m2vs. 12.5 ± 2.3 mF/m2, indicating that SMC could be a potentially useful biomarker for distinguishing malignant and benign human urothelial cells to aid bladder cancer detection.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
用光电动力学装置定量测定正常和癌变人尿路上皮细胞SMC差异
本文报道了利用光电动力学(OEK)装置测量恶性人膀胱癌细胞(RT4)和良性人尿路上皮细胞(sv - huv - 1)的比膜电容(SMC)。实验结果首次表明,RT4细胞(n=54)的SMC明显大于sv - huv - 1细胞(n=48),为15.8±3.5 mF/m2vs。12.5±2.3 mF/m2,提示SMC可能是鉴别人尿路上皮细胞良恶性的潜在生物标志物,有助于膀胱癌的检测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Copyright Information Ferrofluid Levitated Micro/Milli-Robots Implementation Scheme of Orbital Refueling Using Microsate IIite Assembly of Cellular Microstructures into Lobule-Like 3D Microtissues Based on Microrobotic Manipulation* Research supported by the Beijing Natural Science Foundation under Grant 4164099and the National Natural Science Foundation of China under grants 61603044and 61520106011. Three Dimensional Microfabrication Using Local Electrophoretic Deposition Assisted with Laser Trapping Controlled by a Spatial Light Modulator
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1