Fine structural changes in embryonic chick heart ventricle induced by lead poisoning.

S H Gilani
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引用次数: 1

Abstract

The embryonic chick heart ventricle of day 11 was studied electron microscopically to learn the structural changes that develop in lead poisoning. The chick embryos were administered with 0.015 mg/egg of lead acetate at day 2. The most pronounced changes observed in the ventricle were: malformed mitochondria, disorganized, short and scanty myofibrils and abundance of swollen vacuoles. The ultrastructure of the ventricle from the control chick embryos was normal. The most frequent change noted in the ventricular tissue was an alteration in the myofibrils. This study indicates that electron microscopic changes can be induced in the embryonic chick heart ventricle by lead poisoning.

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铅中毒致胚胎鸡心脏心室微细结构改变。
采用电子显微镜观察了铅中毒后第11天胚鸡心脏心室的结构变化。第2天,鸡胚中添加0.015 mg/蛋的醋酸铅。心室最明显的变化是:线粒体畸形,组织紊乱,肌原纤维短而少,空泡肿胀。对照鸡胚心室超微结构正常。心室组织中最常见的改变是肌原纤维的改变。本研究表明,铅中毒可引起胚胎鸡心脏心室的电镜变化。
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