{"title":"Achieving over million-fold fluorescence enhancement for biosensing applications","authors":"L. Velmanickam, I. T. Lima, D. Nawarathna","doi":"10.1109/RAPID49481.2020.9195707","DOIUrl":null,"url":null,"abstract":"We have demonstrated that AC electric fields can be used to amplify the intensity of fluorophore molecules. AC electric fields enhance the metal-fluorophore-light interactions, which produce significant enhancements of fluorescence intensities. This concept can be applied to developing sensitive biosensors for clinical applications.","PeriodicalId":220244,"journal":{"name":"2020 IEEE Research and Applications of Photonics in Defense Conference (RAPID)","volume":"61 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2020 IEEE Research and Applications of Photonics in Defense Conference (RAPID)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/RAPID49481.2020.9195707","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
We have demonstrated that AC electric fields can be used to amplify the intensity of fluorophore molecules. AC electric fields enhance the metal-fluorophore-light interactions, which produce significant enhancements of fluorescence intensities. This concept can be applied to developing sensitive biosensors for clinical applications.
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