Implementation of Workflow Engine on BRIN HPC Infrastructure

Abstract

National Research and Innovation Agency (BRIN)- Indonesia, hosts high performance computing (HPC) facilities to support research and innovation that need high computation resources. One example of a research area is bioinformatics. As sequencing technology advances, any lab with next generation sequencing (NGS) access can generate a huge amount of data in a very short time. However, the difficulties then have shifted to the data analysis step that follows. It usually requires significant computation resources, many specific tools that need to be chained together, and man resources that are familiar with command line syntax. In addition, the chaining of multiple tools into a comprehensive workflow is also difficult since one needs to understand both the computer system administration and biological information related to the problems they try to answer. These hinder the biologist to take advantage of sequencing technology for their research. In this technical report, we described our approaches to integrate Galaxy and BRIN HPC, to ease users to deploy their analysis workflow on BRIN HPC facility.