Pulmonary function profiles in Quebec asbestos workers.

G Fournier-Massey, M R Becklake
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Abstract

Lung function profiles were defined in over 1,000 Quebec chrysotile asbestos workers using five standard tests of lung function, and were related to dust exposure and smoking. Close to half the men (44.3%) had a normal lung function profile and a further 26.5% some function changes but no definite profile. Amongst the remainder restrictive and obstructive function profiles occurred with equal frequency (12.8 and 12.2% respectively). Both were associated with radiologic asbestosis; both occurred infrequently in the absence of the smoking habit. These findings suggest an association between the smoking habit and the harmful effects of asbestos exposure on lung function, and by implication on the development of lung fibrosis. A similar association has been recognized in respect of bronchogenic carcinoma. This experience, in the primary mining and milling of pure chrysotile asbestos, may not be directly applicable to secondary industries concerned with the further processing of this fibre.

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魁北克石棉工人肺功能概况。
使用五项肺功能标准测试确定了1 000多名魁北克温石棉工人的肺功能特征,这些特征与接触粉尘和吸烟有关。接近一半的男性(44.3%)有正常的肺功能,另外26.5%有一些功能改变,但没有明确的特征。其余限制性和梗阻性功能的发生率相同(分别为12.8%和12.2%)。两者都与放射性石棉沉滞有关;在没有吸烟习惯的情况下,这两种情况很少发生。这些发现表明吸烟习惯与石棉暴露对肺功能的有害影响之间存在关联,并暗示了肺纤维化的发展。在支气管源性癌方面也发现了类似的关联。这种在纯温石棉的初级开采和碾磨中的经验,可能不能直接适用于与这种纤维的进一步加工有关的第二工业。
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Proteolytic Mechanisms and Pulmonary Emphysema [A method of continuous recording on microsamples of the Hb-O2 association curve. II. A study of Bohr effect and carbamino-formation (author's transl)]. A method of continuous recording on microsamples of the Hb-O2 association curve. I. Technique and direct registration of standard results. [Relationships of seric IgA and s.IgA of bronchial secretions with respiratory pathophysiology (author's transl)]. Respiratory impairment including assessment of disability. Budapest, Hungary, June 22-26, 1975. 1. Summary of the conference.
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