Alexander J. Gray, Nathan Blanke, Rhiannon E Robinson, D. Rosene, I. Bigio
{"title":"Birefringence Microscope Design and Sample Preparation Exigencies for High-resolution Imaging of Myelin Degradation","authors":"Alexander J. Gray, Nathan Blanke, Rhiannon E Robinson, D. Rosene, I. Bigio","doi":"10.1364/brain.2023.bw1b.5","DOIUrl":null,"url":null,"abstract":"Structural imaging of myelin is of utmost importance for characterization of pathological changes to the brain in neurological disorders. Birefringence microscopy is used for rapid visualization of structural changes to myelin at sub-micron (<300nm) resolution.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"44 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1364/brain.2023.bw1b.5","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Structural imaging of myelin is of utmost importance for characterization of pathological changes to the brain in neurological disorders. Birefringence microscopy is used for rapid visualization of structural changes to myelin at sub-micron (<300nm) resolution.