Ilerhunmwuwa Nosakhare Paul, Hakobyan Narek, A. Henry, Wasifuddin Mustafa, Abowali Hesham, B. Avezbakiyev
{"title":"Possible Lurbinectedin-associated Cardiotoxicity in a Patient with Metastatic Small Cell Lung Cancer: A Case Report","authors":"Ilerhunmwuwa Nosakhare Paul, Hakobyan Narek, A. Henry, Wasifuddin Mustafa, Abowali Hesham, B. Avezbakiyev","doi":"10.29011/28333497.000152","DOIUrl":null,"url":null,"abstract":"Background: It has been a major challenge finding an effective second-line therapy with a favorable safety profile for metastatic small cell lung cancer (SCLC) in patients who failed or relapsed following first-line platinum-based chemotherapy. Lurbinectedin was approved for SCLC in patients who relapsed or failed first-line treatment. The most common adverse event associated with it was myelosuppression. Till date, no cardiotoxicity has been described with this medication in the literature.","PeriodicalId":254574,"journal":{"name":"Annals of Medical and Clinical Oncology","volume":"39 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Medical and Clinical Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.29011/28333497.000152","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Background: It has been a major challenge finding an effective second-line therapy with a favorable safety profile for metastatic small cell lung cancer (SCLC) in patients who failed or relapsed following first-line platinum-based chemotherapy. Lurbinectedin was approved for SCLC in patients who relapsed or failed first-line treatment. The most common adverse event associated with it was myelosuppression. Till date, no cardiotoxicity has been described with this medication in the literature.
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