Review Report on Natural Products as Anti-Fungal Agents

Somia Gul
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Abstract

Human fungal infections have been greatly increasing nowadays mainly, in patients of cancer, AIDS and those that are immunecompromised. Therefore, the usage of anti-fungal drugs has also been increased, resulting in resistance to the currently available drugs. The resistance to anti-fungal drugs has an inference to the health of the community. As the currently used anti-fungal drugs have limited effective activity, more drug-drug interactions, and toxicity issues, it seems essential to identify therapeutic options for fungal infections. Discovering new anti-fungal compounds from the natural products like plants could provide a significant source for new medicinal products. This review discusses the currently available natural products reported as antifungal agents, current status of those products, as well as, advancement and future perspective of natural products as anti-fungal agents.
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天然产物作为抗真菌剂的研究综述
目前,人类真菌感染已大大增加,主要发生在癌症、艾滋病和免疫功能低下的患者中。因此,抗真菌药物的使用也增加了,导致对现有药物的耐药性。抗真菌药物的耐药性影响到社会的健康。由于目前使用的抗真菌药物具有有限的有效活性,更多的药物-药物相互作用和毒性问题,因此确定真菌感染的治疗方案似乎至关重要。从植物等天然产物中发现新的抗真菌化合物可以为新药物提供重要来源。本文综述了目前报道的天然抗真菌药物,天然抗真菌药物的研究现状,以及天然抗真菌药物的研究进展和未来展望。
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