Study of Antibacterial and Antifungal Activities of Schiff Base Complexes of Co (II) and Cu (II) Derived from Salicyldehyde and Diphenylamine

Abstract

Abstract: This paper reports antibacterial and antifungal activities of Schiff base and that’s of its metal (II) complexes (Co, Cu) derived from salicyldehyde and diphenylamine. The Schiff base and its metal (II) complexes were characterized using different analytical techniques like FTIR, melting point, solubility, and molar conductance, The Schiff base and its respective metals complexes were colored. The result from IR analysis revealed bands at 1614cm-1 indicating the formation of azomethine (C=N) confirming the formation of Schiff base. The band at 664cm-1 indicate the formation of complex which is assign to V(M-N) supporting coordination of Schiff base to respective metals. The solubility test result showed that both the Schiff base and complexes are soluble in most organic solvent and insoluble in water. Both the schiff base and complexes revealed sharp melting point and decomposition temperature. The molar conductance data of the complexes in Dimethylsulphoxide (DMSO) show low value of 9 and 10 Ohm-1cm2 mol-1) indicating the complexes are non-electrolytes. The entire compounds were tested for their antibacterial and antifungal activities. The results indicated that the growth of the tested organism was inhibited by the compounds.