{"title":"In Silico Assessment of Nanosecond Pulse Exposures of Cells, Tissues and Organs","authors":"T. Gowrishankar, A. Esser, K. Smith, J. Weaver","doi":"10.1109/MODSYM.2006.365295","DOIUrl":null,"url":null,"abstract":"We have developed an in silico framework that integrates macro- and microdosimetry models, and incorporates biophysical mechanism models to estimate biochemical change resulting from exposure to nanosecond electrical pulses. This approach provides estimates of conductance changes and biochemical release/uptake within cells, local tissue regions and organs","PeriodicalId":410776,"journal":{"name":"Conference Record of the 2006 Twenty-Seventh International Power Modulator Symposium","volume":"8 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2006-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Conference Record of the 2006 Twenty-Seventh International Power Modulator Symposium","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/MODSYM.2006.365295","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
We have developed an in silico framework that integrates macro- and microdosimetry models, and incorporates biophysical mechanism models to estimate biochemical change resulting from exposure to nanosecond electrical pulses. This approach provides estimates of conductance changes and biochemical release/uptake within cells, local tissue regions and organs