A New Repeat Family Detection Method Based on Sparse de Bruijn Graph

Hong Zhou, Zheng Zhao, Hongpo Wang
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Abstract

Eukaryotic genomes are typically large and filled with both genes and multiple classes of repetitive DNA. The repetitive DNAs are a rapidly evolving genome component that can provide the raw material for novel selected functions and also indicate the mechanisms and history of genome evolution in any ancestral lineage. In order to facilitate a broader range of repeat analyses, we present a graph method for repeat family detection and characterization by using the sparse de Bruijn graphs. This program was written in JAVA and with numerous adjustable parameters. Testing of this program indicated that it can found all of the major repeats.
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基于稀疏de Bruijn图的重复族检测新方法
真核生物的基因组通常很大,充满了基因和多种类型的重复DNA。重复dna是一种快速进化的基因组成分,可以为新的选择功能提供原料,也可以指示任何祖先谱系中基因组进化的机制和历史。为了便于更广泛的重复分析,我们提出了一种利用稀疏de Bruijn图进行重复家族检测和表征的图方法。这个程序是用JAVA编写的,有许多可调参数。该程序的测试表明,它可以发现所有的主要重复。
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