Management of Trapped Fourth Ventricle in Patient with Cerebral and Spinal Neurocysticercosis

Tracy S. Ma, Benjamin A. Rubin, B. Grobelny, Robert E. Elliott, D. Zagzag, D. Harter, I. Mikolaenko
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Abstract

Neurocysticercosis (NCC) is the most common parasitic infection of the CNS. Surgical intervention is often required to treat for hydrocephalus with neuroendoscopy emerging as a logical alternative to craniotomies. While cranial NCC cases have increased in the United States, spinal NCC incidences have remained relatively low. We report a case of trapped fourth ventricle and myelopathy from both concomitant cranial and spinal NCC. This patient exhibited a subacute thoracic myelopathy and acute deterioration from a trapped fourth ventricle (TFV) from aqueductal and fourth ventricular outflow occlusion. She underwent urgent posterior fossa exploration. A fourth ventricular lesion consistent with NCC was removed from the distal aqueduct and the aqueduct was opened via aqueductoplasty with a ventricular catheter and balloon dilatation. She improved following surgery without extraoccular dysfunction. Intraoperative visualization and postoperative MRI flow-studies confirmed patency of the aqueduct and there was complete resolution of her fourth ventricle dilatation. With antiparasitic and corticosteroid therapy, her myelopathy has slowly improved over 9 months of follow-up.
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脑脊神经囊虫病患者第四脑室截留的处理
神经囊虫病(NCC)是最常见的中枢神经系统寄生虫感染。手术干预往往需要治疗脑积水与神经内窥镜出现作为一个合乎逻辑的替代开颅手术。在美国,颅脑NCC病例有所增加,而脊髓NCC的发病率仍然相对较低。我们报告一个病例受困的第四脑室和脊髓病从合并颅和脊髓NCC。该患者表现为亚急性胸椎脊髓病,并因输水管和第四心室流出堵塞导致第四脑室(TFV)被困而急性恶化。她接受了紧急后窝探查。第四个心室病变符合NCC从远端导水管切除,并通过导水管成形术与心室导管和球囊扩张打开导水管。术后病情好转,无眼外功能障碍。术中可视化和术后MRI血流检查证实导水管通畅,第四脑室扩张完全消除。在抗寄生虫和皮质类固醇治疗下,她的脊髓病在9个月的随访中缓慢改善。
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