Thrombokinetics in systemic lupus erythematosus A preliminary report.

Pahlavi medical journal Pub Date : 1976-04-01
A L Bergström, J Kutti, S Safai-Kutti
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Abstract

Twelve non-thrombocytopenic patients ( 3 males and 9 females) with systemic lupus erythematosus (SLE) were investigated with respect to platelet size, percentage of megathrombocytes, platelet survival and platelet production. The values for platelet size and percentage of megathrombocytes did not differ from those of a control group. In the SLE group the mean platelet MLS was identical to the control mean, and all patients with SLE had values for platelet MLS within the range of the control subjects. All SLE patients but one had values for platelet turnover within the control range. For unclear reason one single SLE patient had a moderately elevated platelet turnover value. The results of the present investigation do not support the theory that a state of compensated thrombocytolysis is present in SLE.

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系统性红斑狼疮的血栓动力学初步报告。
研究了12例系统性红斑狼疮(SLE)非血小板减少性患者(男3例,女9例)的血小板大小、大血小板百分比、血小板存活率和血小板生成情况。血小板大小和巨凝细胞百分比的值与对照组没有差异。SLE组的平均血小板MLS与对照组的平均相同,所有SLE患者的血小板MLS值都在对照组的范围内。除1例外,所有SLE患者的血小板周转率均在控制范围内。不清楚的原因,单个SLE患者有中度升高的血小板周转值。目前的研究结果不支持在SLE中存在代偿性溶栓状态的理论。
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