Asthma and Inflammation

A. Chan
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Abstract

Asthma is a chronic inflammatory airway disease, for which the cornerstone of asthma therapy is inhaled corticosteroids. however, long term clinical outcomes are variable, and not all patients respond optimally to corticosteroids. Underpinning this observation is that asthma is a heterogeneous disease consisting of phenotypes that are driven by different inflammatory pathways. In this article, we will discuss the different inflammatory mechanisms of asthma to better define patient characteristics and help improve patient outcomes with newer specific-targeted asthma therapies.
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哮喘和炎症
哮喘是一种慢性炎症性气道疾病,哮喘治疗的基石是吸入皮质类固醇。然而,长期的临床结果是可变的,并不是所有的患者对皮质类固醇反应最佳。支持这一观察结果的是,哮喘是一种异质性疾病,由不同炎症途径驱动的表型组成。在本文中,我们将讨论哮喘的不同炎症机制,以更好地定义患者特征,并帮助通过新的特异性靶向哮喘治疗改善患者的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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