Detectable Antibodies in Newborn Cord Blood Following Maternal COVID-19 Infection Before Pregnancy: A Case Report

Abstract

: In this report, we present a case of an infant with detectable antibodies in the umbilical cord blood who was born to a healthcare professional mother diagnosed with coronavirus disease 2019 (COVID-19) before pregnancy and recovered, and also discuss the antibody level in light of relevant literature. Data consisted of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) polymerase chain reaction (PCR) test and negative pre-pregnancy repeat real-time polymerase chain reaction (RT-PCR) test of a 29-year-old medical doctor mother, follow-up antibody test results in pregnancy, and antibodies detected in the cord blood of the newborn after birth. The study data were collected through face-to-face interviews with the mother. In conclusion, this case shows that SARS-CoV-2 immunoglobulin G (IgG) antibodies can be detected in the baby’s cord blood immediately after birth from a mother who was diagnosed with COVID-19 before becoming pregnant and subsequently recovered with pharmacological treatment.