CLINICAL MANIFESTATION OF COVID-19 CO-INFECTION CASE IN BENGKULU CITY

Debie Rizqoh, Enny Nugrahaeni, Jusup Endang, M. Sundari, Dessy Triana, M. Sariyanti, Nikki Aldi Massardi
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Abstract

Background: The COVID-19 pandemic is still ongoing, and no one could predict when it would end. In some cases of COVID-19, patients experienced infection by SARS-Cov-2 and other microorganisms, including viruses, bacteria, and fungi.Objective: This study aims to determine Co-infection on clinical symptoms and mortality of COVID-19 patients in Bengkulu City, Indonesia.Methods: We reviewed and analyzed data on patients with confirmed COVID-19 who were co-infected, including basic information, clinical manifestations, radiological and laboratory examinations, to the final status.Results: A total of 105 patients with confirmed COVID-19 participated in this study with various clinical manifestation: mild case (12%), moderate case/ mild pneumonia (52%), severe pneumonia (20%) and critical case (16%). Of the 105 patients, six patients were co-infected with human immunodeficiency virus (HIV) (1 case), Mycobacterium tuberculosis (2 cases), Salmonella thypii (2 cases), bacterial pneumonia, and viral pneumonia (1 case). As many as three of the six patients experienced inferior clinical manifestations and died.Conclusion: The co-infection of other microorganisms in COVID-19 can affect the severity and mortality in COVID-19 patients.
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明古鲁市新冠肺炎合并感染病例临床表现分析
背景:COVID-19大流行仍在持续,没有人能预测它何时会结束。在某些COVID-19病例中,患者感染了SARS-Cov-2和其他微生物,包括病毒、细菌和真菌。目的:本研究旨在了解合并感染对印度尼西亚明古鲁市COVID-19患者临床症状和死亡率的影响。方法:对合并感染的新冠肺炎确诊患者的基本信息、临床表现、影像学和实验室检查等资料进行回顾性分析,直至最终状态。结果:本次研究共纳入确诊COVID-19患者105例,临床表现多样:轻症(12%)、中/轻肺炎(52%)、重症肺炎(20%)、危重症(16%)。105例患者中,共感染人类免疫缺陷病毒(HIV) 1例、结核分枝杆菌2例、伤寒沙门菌2例、细菌性肺炎、病毒性肺炎1例。6例患者中有3例临床表现不佳而死亡。结论:合并感染其他微生物可影响COVID-19患者的严重程度和死亡率。
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