Screening of Antibacterial Potential and Phytochemical Analysis of Medicinal Plant Barleria Prionitis

S. Tyagi, Sanjeev Kumar, Ashish S. Kumar
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Abstract

Medicinal and healing proper- ties of herbs are closely related to their chemical components which are classified into some major groups like alkaloids, phenols, terpenoids, steroids, saponins, tannins etc. and getting these chemicals out into the herbal remedy depends upon the solubility of these compounds in various solvents. In the present study aqueous ethanol diethyl ether acetone and methanol extracts of Barleria prionitis leaves were investigated for phyto-chemical and anti-microbial activity. The micro-organisms employed were Staphylococcus aureus Escherichia coli,and Pseudomonas, aeruginosa and Bacillus subtilis. The susceptibility of bacterial strains against the all extracts was determined using the disk diffusion method. The findings showed that potential antibacterial properties of the extracts against the organisms tested. The most susceptible microorganisms were S. aureus, while the least susceptible was E. coli. Aqueous extracts had no activity against the test bacteria the leaves of plant were found abundant with biologically active phytochemicals.
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药用植物朊芽孢杆菌抑菌潜力筛选及植物化学分析
草药的药用和治疗功能与它们的化学成分密切相关,这些化学成分被分为几大类,如生物碱、酚类、萜类、类固醇、皂苷、单宁等,将这些化学物质提取到草药中取决于这些化合物在各种溶剂中的溶解度。本文研究了朊芽孢杆菌叶的乙醇、乙醚、丙酮和甲醇提取物的植物化学活性和抑菌活性。所采用的微生物有金黄色葡萄球菌、大肠杆菌、假单胞菌、铜绿杆菌和枯草芽孢杆菌。采用纸片扩散法测定菌株对各提取物的敏感性。研究结果表明,提取物对测试的微生物具有潜在的抗菌特性。最敏感的是金黄色葡萄球菌,最不敏感的是大肠杆菌。水提液对试验细菌无活性,而植物叶片中含有丰富的生物活性化学物质。
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