The Effect of Duration of Laser Radiation with the Same Dose in the Treatment of Recurrent Aphthous Stomatitis

Farzaneh Aghakhani, A. Shirani, N. Amini
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Abstract

Introduction: Recurring aphthous ulcers is a common and painful ulcer in the oral area. The aim of this study was to evaluate the impact of length of radiation in the same dose for the treatment of recurrent aphthous stomatitis. To date no similar study is available. Materials & Methods: In this double-blinded clinical trial, 30 patients with minor aphthous ulcer that were referred to Oral medicine department of Islamic Azad university were selected according to convenience sampling and inclusion exclusion criteria and were randomly divided into two similar groups. Low level laser therapy with diode 660nm was used in group A with 200 mW and 20 seconds setting and in group B with 20 mW and 200 seconds setting in two sessions on the first and third days were used. The time of clinical healing and the pain intensity as VAS were recorded. Data were analyzed by Independent t-test and Mann-Whitney test (p value < 0.05). Results: The pain intensity from first day after the laser until the seventh day in group B was significantly less than group A (p value < 0.001). The mean size of lesion was significantly lower in the third day (p value = 0.03), fifth (p value < 0.001) and seventh (p value = 0.001). The mean clinical healing time in group B was significantly lower than group A (p value < 0.001). Conclusion: According to this study's findings, longer time of irradiation in lower output power of 660 nm diode laser was suggested for treatment of recurrent aphthous ulcer.
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相同剂量激光照射时间对复发性口腔炎的影响
简介:复发性口腔溃疡是一种常见的口腔溃疡。本研究的目的是评估相同剂量下放射时间长短对治疗复发性口疮性口炎的影响。到目前为止还没有类似的研究。材料与方法:本双盲临床试验选取30例转诊至伊斯兰阿扎德大学口腔内科的轻度阿弗顿溃疡患者,按照方便抽样和纳入排除标准随机分为相近的两组。A组采用200 mW、20秒设定,B组采用20 mW、200秒设定,分第1天和第3天进行2次治疗。分别记录临床愈合时间和疼痛强度。资料分析采用独立t检验和Mann-Whitney检验(p值< 0.05)。结果:B组患者术后第1天至第7天疼痛强度明显低于A组(p值< 0.001)。病变的平均大小在第3天(p值= 0.03)、第5天(p值< 0.001)和第7天(p值= 0.001)显著降低。B组平均临床愈合时间显著低于A组(p值< 0.001)。结论:根据本研究结果,建议采用较长时间低输出功率的660 nm二极管激光照射治疗复发性阿弗顿溃疡。
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