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The Ability of Mesenchymal Stem Cells for Periodontal Tissue Regeneration: A Comprehensive Review of Literature 间充质干细胞对牙周组织再生的能力:文献综述
Pub Date : 2023-03-07 DOI: 10.18502/ijds.v18i4.12110
MohammadMostafa Aghamohseni, S. Farhad
Introduction: Stem cells and tissue engineering have shown great potential in the treatment of periodontal diseases since their introduction. Mesenchymal stem cells are undifferentiated cells that can differentiate into different tissues. The aim of this study was to evaluate the effectiveness of different types of these cells in the treatment of periodontal defects.Description: Mesenchymal stem cells exist around different tissues and can be obtained and used from different intraoral or extraoral sources for periodontal tissue regeneration procedures. Among extracellular stem cells, bone marrow stem cells followed by adipose tissue stem cells have shown promising results regarding the ability of these cells to regenerate the periodontium. Among intraoral sources, periodontal ligament mesenchymal stem cells and then dental pulp cells have shown more results and ability compared to other cell types to regenerate periodontal tissue. Periodontal ligament stem cells have also been able to generate sharpey fibers in periodontal regeneration procedures in various studies.Conclusion: Mesenchymal stem cells have shown promising results for use in periodontal tissue regeneration processes. However, due to the limited clinical and preclinical studies performed so far, more studies are needed for assessing the clinical use of these generative of cells.
干细胞和组织工程技术自问世以来,在牙周病的治疗中显示出巨大的潜力。间充质干细胞是未分化的细胞,可以分化成不同的组织。本研究的目的是评估不同类型的这些细胞在治疗牙周缺损中的有效性。描述:间充质干细胞存在于不同的组织周围,可以从不同的口腔内或口腔外来源获得并用于牙周组织再生手术。在细胞外干细胞中,骨髓干细胞随后是脂肪组织干细胞,这些细胞再生牙周组织的能力显示出有希望的结果。在口腔内来源中,牙周韧带间充质干细胞和牙髓细胞在牙周组织再生方面比其他类型的细胞表现出更多的效果和能力。在各种研究中,牙周韧带干细胞也能够在牙周再生过程中产生尖锐的纤维。结论:间充质干细胞在牙周组织再生中具有良好的应用前景。然而,由于迄今为止进行的临床和临床前研究有限,需要更多的研究来评估这些生殖细胞的临床应用。
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引用次数: 0
Immunohistochemical Expression of Alpha Smooth Muscle Actin Positive Myofibroblast and Laminin 5 gamma 2 in Squamous Cell Carcinoma and Verrucous Carcinoma of the Oral Cavity α -平滑肌肌动蛋白阳性肌成纤维细胞和层粘连蛋白5 - 2在口腔鳞状细胞癌和疣状癌中的免疫组织化学表达
Pub Date : 2023-03-07 DOI: 10.18502/ijds.v18i4.12096
Homeyra Mardani, Bahareh Rashnavadi, N. A. Moghadam
Introduction: Squamous cell carcinoma is the most common type of oral cancer that shows certain tissue changes. Laminin-5γ2 is a protein that plays a central role in migration of the neoplastic cells during tumor invasion. Expression of this protein in cells and stroma adjacent to tumor can confirm the cellular invasion. The aim of this study was to evaluate stroma in verrucous carcinoma and squamous cell carcinoma of the mouth using two markers α SMA and laminin 5 gamma 2.Materials & Methods: In this retrospective descriptive-analytical study, 60 samples were selected with the diagnosis of squamous cell carcinoma and verrucous oral carcinoma. Then, two markers of α SMA and laminin 5 gamma 2 were examined in epithelium and mesenchymal stroma by immunohistochemistry. The vasculature was used as a positive immunoreactivity control for alpha-smooth muscle and the normal mucosa was used to control the positive immunoreactivity of laminin 5 gamma 2. The results were analyzed using Chi-square and Spearman correlation tests (α = 0.05).Results: Out of 31 SCC samples, 80.6% showed laminin 5 gamma 2 and 90.3% showed alpha smooth and out of 9 samples of varocus carcinoma, 66.7% showed laminin 5 gamma 2 and 77.8% showed alpha smooth actin. The higher the positive percentage of laminin, the higher the percentage of positive α SMA.Conclusion: Expression of alpha smooth muscle actin and lamminin 5 gamma 2 was significantly higher in oral squamous cell carcinoma and there exists a correlation between expression of alpha smooth muscle actin and the increase in myofibroblasts takes place during the carcinogenesis process.
简介:鳞状细胞癌是最常见的口腔癌类型,表现出一定的组织改变。laminin -5γ - 2是一种在肿瘤侵袭过程中肿瘤细胞迁移中起核心作用的蛋白。该蛋白在肿瘤邻近细胞和基质中的表达可以证实细胞的侵袭。本研究的目的是用两种标志物α SMA和层粘连蛋白5 γ 2评价口腔疣状癌和鳞状细胞癌的间质。材料与方法:本回顾性描述性分析研究选择60例诊断为口腔鳞状细胞癌和疣状癌的病例。免疫组化法检测上皮和间充质间质α - SMA和层粘连蛋白5 - γ 2两种标志物。以血管作为α -平滑肌的阳性免疫反应对照,以正常黏膜作为层粘连蛋白5 - γ - 2的阳性免疫反应对照。采用χ 2检验和Spearman相关检验对结果进行分析(α = 0.05)。结果:31例SCC样本中,80.6%的样本显示层粘连蛋白5 - γ - 2, 90.3%的样本显示α光滑;9例静脉曲张癌样本中,66.7%的样本显示层粘连蛋白5 - γ - 2, 77.8%的样本显示α光滑肌动蛋白。层粘连蛋白阳性率越高,α - SMA阳性率越高。结论:α -平滑肌肌动蛋白和lamminin 5 - γ - 2在口腔鳞状细胞癌中的表达明显升高,α -平滑肌肌动蛋白的表达与癌变过程中肌成纤维细胞的增加存在相关性。
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引用次数: 0
Cytotoxicity Effects of Polyhydroxybutyrate/Chitosan/Bioglass Nanocomposite Scaffolds on Human Osteoblast-like Cells (SAOS-2 Cells) 聚羟基丁酸/壳聚糖/生物玻璃纳米复合支架对人成骨样细胞(SAOS-2)的细胞毒性作用
Pub Date : 2023-03-07 DOI: 10.18502/ijds.v18i4.12103
Batool Hashemi-Beni, M. Khoroushi, Saeed Karbasi, F. Heidari, Mohamad Reza Foroughi
Introduction: In tissue engineering, a porous material is applied as the extracellular matrix or scaffold for cell growth. Then growth factors are added to this scaffold whose cytotoxicity must be assessed. In this study, the cytotoxicity effects of polyhydroxybutyrate/chitosan/bioglass nanocomposite scaffolds on human osteoblast like cells (SAOS-2 cells) are explored.Materials & Methods: This study was experimental and was done in Isfahan Dental School. The polyhydroxybutyrate/chitosan/bioglass nanocomposite scaffold was fabricated using the electrospinning method. Scanning Electron Microscopy (SEM) analysis was used to evaluate the morphological characteristics of the nanofibers and their diameter distribution. Additionally, bioglass nanoparticles in the fibers were identified via SEM. The MTT assay was performed to assess cell viability after 3, 5, and 7 days. The collected data were analyzed using SPSS 20.0 through statistical tests including Kruskal-Wallis test (p value ≤ 0.05).Results: According to SEM images, the scaffold fibers were fully porous and no beads were observed. Furthermore, the polyhydroxybutyrate/chitosan/bioglass scaffold showed greater cell viability and proliferation compared to the groups lacking bioglass.Conclusion: The polyhydroxybutyrate/chitosan/bioglass scaffold has no cytotoxic effect on osteoblast– like cells.
在组织工程中,多孔材料被用作细胞外基质或细胞生长的支架。然后将生长因子添加到支架中,必须评估其细胞毒性。本研究探讨了聚羟基丁酸/壳聚糖/生物玻璃纳米复合支架对人成骨样细胞(SAOS-2细胞)的细胞毒性作用。材料与方法:本研究是实验性的,在伊斯法罕牙科学校完成。采用静电纺丝法制备了聚羟基丁酸酯/壳聚糖/生物玻璃纳米复合支架。利用扫描电镜(SEM)分析了纳米纤维的形态特征及其直径分布。此外,通过扫描电镜鉴定了纤维中的生物玻璃纳米颗粒。在3、5和7天后进行MTT试验评估细胞活力。收集的资料采用SPSS 20.0软件进行统计学分析,采用Kruskal-Wallis检验(p值≤0.05)。结果:扫描电镜显示,支架纤维多孔,无微珠。此外,与缺乏生物玻璃的组相比,聚羟基丁酸/壳聚糖/生物玻璃支架具有更高的细胞活力和增殖能力。结论:聚羟基丁酸/壳聚糖/生物玻璃支架对成骨样细胞无细胞毒性作用。
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引用次数: 0
Treatment of Severe Anterior Open-bite Accompany with Impacted Canine: A Case Report 严重前牙开咬伴阻生犬1例
Pub Date : 2023-03-07 DOI: 10.18502/ijds.v18i4.12112
Fataneh Ghorbanyjavadpour
Introduction: The anterior open bite is a multifactorial malocclusion and a challenge between orthodontists. Based on the origin, divided in two types as dental and skeletal, and appear in the anterior or posterior segments, (unilateral or bilateral). Dental open-bite in the most of patients have environmental etiologic factor such as oral habits, tongue trust, mouth breathing, large tongue. In skeletal type, excessive vertical growth of the maxilla is etiologic factor and accompany with downward-backward rotation of the mandible.Case Report: The case was a 27 years woman with an anterior open bite and unilateral impacted upper canine and congenital missing of lower 2nd premolar in the left side and retained 2nd lower deciduous molar and upper canine in the left side. She consulted for orthodontic treatment in Tehran Dental School of Shahid Beheshti University of Medical Sciences in October of 2017.The Orthodontic treatment was down with MBT slot 22 system (USA. Orthoorganizer, inc) for apply extrusive force on impacted upper canine in left side with auxiliary 014 ss, segmented arch wire. loop arch wire technique with 16 × 22 ss rectangular continuous arch wire was used for space closing in extraction site and correction overbite. The extracted teeth were right lower 2nd premolar and left 2nd deciduous molar and 1st premolars in upper arch. As recommended advancement genioplasty for correction chin deficiency the patient refused it. Conclusion: In this technique we used Orthodontic treatment alone instead of Orthognathic surgery for open bite correction.
前言:前开咬合是一种多因素错牙合,是正畸医师面临的挑战。根据起源,分为牙齿和骨骼两种类型,并出现在前节或后节,(单侧或双侧)。口腔开咬患者大多有环境病因,如口腔习惯、舌信、口呼吸、舌大等。在骨型中,上颌过度垂直生长是病因,并伴有下颌骨向下向后旋转。病例报告:该病例是一名27岁的女性,患有前牙开咬和单侧上犬牙阻生,先天性左侧下第二前磨牙缺失,左侧保留第二下乳牙和上犬牙。她于2017年10月在Shahid Beheshti医学科学大学德黑兰牙科学校进行正畸治疗咨询。正畸治疗采用MBT 22槽系统(美国)。矫形器(Orthoorganizer, inc)用辅助的014ss分段弓丝对左侧的上犬齿施加挤压力。环形弓丝技术采用16 × 22 s矩形连续弓丝进行拔牙部位空隙闭合和复咬修复。拔除的牙齿为右下第二前磨牙、左第二乳牙和上弓第一前磨牙。建议采用颏部成形术矫正颏部缺陷,但患者拒绝。结论:采用单纯的正畸治疗代替正颌手术进行开咬矫正。
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引用次数: 0
Evaluation of the Relationship between rs17561 and rs1143634 Genetic Polymorphisms and the Risk of Chronic Periodontitis rs17561和rs1143634基因多态性与慢性牙周炎发病风险的关系
Pub Date : 2023-03-07 DOI: 10.18502/ijds.v18i4.12099
J. Yaghini, Amir Farmohammadi, M. Karimian, M. Jamshidi
Introduction: Genetic diversity in cytokines such as interleukin α1 and interleukin 1β is involved in altering the immune response in inflammatory diseases such as chronic periodontitis and changes the risk of this disease. The aim of this study was to investigate the association of genetic polymorphisms 4845G> T interleukin 1α and 3954C> T interleukin 1β with the risk of chronic periodontitis.Materials & Methods: Participants including 133 healthy individuals and 133 individuals with chronic periodontitis referred to Isfahan Dental School, were included in the study. The genotype of blood samples at the site of the above polymorphism was determined by PCR-RFLP method. The relationship between the studied polymorphisms and chronic periodontitis was calculated by logistic regression test. Statistical analyzes were performed by SPSS software. The p value level < 0.05 was statistically significant.Results: Data analysis showed a significant relationship between CT and TT genotypes and T allele of polymorphism 3954C> T interleukin 1β and increased risk of chronic periodontitis and no significant relationship between polymorphism 4845G> T of interleukin 1α and the risk of Showed chronic periodontitis.Conclusion: Based on the above data, T> 3954C polymorphism is a risk factor for chronic periodontitis and serves as a potential biomarker for screening people prone to this disease.
导论:白细胞介素α1和白细胞介素1β等细胞因子的遗传多样性参与改变慢性牙周炎等炎症性疾病的免疫反应,并改变该疾病的风险。本研究旨在探讨遗传多态性4845G> T白细胞介素1α和3954C> T白细胞介素1β与慢性牙周炎风险的关系。材料与方法:研究对象包括133名健康个体和133名伊斯法罕牙科学校的慢性牙周炎患者。采用PCR-RFLP法测定上述多态性位点的血样基因型。通过logistic回归检验计算所研究的多态性与慢性牙周炎的关系。采用SPSS软件进行统计学分析。p值水平< 0.05有统计学意义。结果:数据分析显示,CT和TT基因型及白细胞介素1β多态性3954C> T等位基因与慢性牙周炎发病风险增加有显著相关性,白细胞介素1α多态性4845G> T与慢性牙周炎发病风险无显著相关性。结论:基于以上数据,T> 3954C多态性是慢性牙周炎的危险因素,可作为筛查慢性牙周炎易发人群的潜在生物标志物。
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引用次数: 0
Investigation of Morphological Variations of Canal and Root of First Mandibular Molar in Tomographic Images Computer with Cone Beam in Patients of Arak City 阿拉克市患者下颌第一磨牙根管形态变化的锥形束计算机断层成像研究
Pub Date : 2023-03-07 DOI: 10.18502/ijds.v18i4.12100
Mahsa Kianifar
Introduction: Being the first teeth to erupt, first molars have the most complex root system and canal morphology and are among the most susceptible teeth to decay and destruction. The aim of this study is to determine the frequency of morphological variations of the canal and root of the mandibular first molar in cbct images so that appropriate treatment can be performed with a better understanding of the anatomy of the root and canal of the molar tooth.Materials & Methods: In this descriptive cross-sectional study, the morphological variation of the mandibular first molar canal and root was investigated in 170 cbct radiology image samples. In this study, the age and gender of the individual, the number of roots and canals of the mandibular first molar, the morphology of the canal in each root, the presence of the midmesial canal and the presence of the distolingual root were also investigated. In the end, frequency and percentage indicators were used to analyze data and chi-square test was used to compare frequencies.Results: The average age of the subjects studied was 39.2 years. The subjects included 86 women and 84 men. The most seen sample was a molar tooth with two roots and three canals. In terms of canal morphology in the mesial root, the most common canal morphology was type 4 and then type 2. In terms of canal morphology in the distal root, the most common canal morphology was type 1. In the studied samples, midmesial canal was not found in 99.4% of cases and distolingual root was not found in 94.7% of cases.Conclusion: Two-rooted and three-channel molar without midmesial canal and without distolingual root was the most common case found in this study. The most common canal morphology in the mesial root was type 4 and the most common canal morphology in the distal root was type 1.
第一磨牙是人类最早长出的牙齿,具有最复杂的牙根系统和牙根管形态,是最容易被腐蚀和破坏的牙齿之一。本研究的目的是确定cbct图像中下颌第一磨牙根管和根的形态变异频率,以便在更好地了解磨牙根管解剖结构的基础上进行适当的治疗。材料与方法:在本描述性横断面研究中,对170张ct影像样本进行了下颌第一磨牙管和牙根的形态学变化研究。在这项研究中,还调查了个体的年龄和性别,下颌第一磨牙的根和管的数量,每个根的管的形态,是否存在中根和双舌根。最后采用频率和百分比指标对数据进行分析,并采用卡方检验对频率进行比较。结果:研究对象平均年龄39.2岁。研究对象包括86名女性和84名男性。最常见的样本是一颗有两根和三条牙管的臼齿。中根管形态以4型居多,其次为2型。在远端根管形态方面,最常见的根管形态为1型。在研究样本中,99.4%的病例未发现中管,94.7%的病例未发现双舌根。结论:无中根、无双舌根的双根三通道磨牙是本研究中最常见的病例。中根最常见的根管形态为4型,远根最常见的根管形态为1型。
{"title":"Investigation of Morphological Variations of Canal and Root of First Mandibular Molar in Tomographic Images Computer with Cone Beam in Patients of Arak City","authors":"Mahsa Kianifar","doi":"10.18502/ijds.v18i4.12100","DOIUrl":"https://doi.org/10.18502/ijds.v18i4.12100","url":null,"abstract":"Introduction: Being the first teeth to erupt, first molars have the most complex root system and canal morphology and are among the most susceptible teeth to decay and destruction. The aim of this study is to determine the frequency of morphological variations of the canal and root of the mandibular first molar in cbct images so that appropriate treatment can be performed with a better understanding of the anatomy of the root and canal of the molar tooth.Materials & Methods: In this descriptive cross-sectional study, the morphological variation of the mandibular first molar canal and root was investigated in 170 cbct radiology image samples. In this study, the age and gender of the individual, the number of roots and canals of the mandibular first molar, the morphology of the canal in each root, the presence of the midmesial canal and the presence of the distolingual root were also investigated. In the end, frequency and percentage indicators were used to analyze data and chi-square test was used to compare frequencies.Results: The average age of the subjects studied was 39.2 years. The subjects included 86 women and 84 men. The most seen sample was a molar tooth with two roots and three canals. In terms of canal morphology in the mesial root, the most common canal morphology was type 4 and then type 2. In terms of canal morphology in the distal root, the most common canal morphology was type 1. In the studied samples, midmesial canal was not found in 99.4% of cases and distolingual root was not found in 94.7% of cases.Conclusion: Two-rooted and three-channel molar without midmesial canal and without distolingual root was the most common case found in this study. The most common canal morphology in the mesial root was type 4 and the most common canal morphology in the distal root was type 1.","PeriodicalId":221865,"journal":{"name":"Journal of Isfahan Dental School","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116207960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Diagnostic Accuracy of 2 Cone Beam Computed Tomography System (Newtom &Planmeca) for Detection of External Root Resorption in Vitro 2锥束计算机断层扫描系统(Newtom &Planmeca)体外检测外根吸收诊断准确性的比较
Pub Date : 2023-03-07 DOI: 10.18502/ijds.v18i4.12097
M. Bolbolian, M. Esfehani, N. Hajihassani, Z. Khalili, M. Mobini, M. Tofangchiha
Introduction: External root resorption is a clinical problem that is difficult to diagnose, therefore radiographic examination is important for diagnose. The purpose of this study was comparing the diagnostic accuracy of 2 Cone Beam Computed Tomography in detecting of external root resorption, in vitro.Materials & Methods: This study was done on 48 single-rooted teeth. Cavities of 0.3, 0.2 and 0.15 mm in depth with round bur 0.3 mm were drilled on buccal and lingual surfaces in the cervical, middle and apical thirds of some of roots. Then CBCT were taken and 4 observers assessed the scans. Sensitivity, specificity and Kappa value were determined. The statistical analysis was performed with the Z-test (p value < 0.05).Results: In comparison of the accuracy, sensitivity and specificity of the two devices, there was no significant difference. In the apical, middle and cervical as well as at various depths there was no significant difference between the two devices, but in the numerical point of view, the sensitivity for both devices in the midsection, was in the highest amount. The highest value for the specificity is related to the apical region. For both devices, the sensitivity level GBJ, by increasing the depth. The lowest agreement between observers was 0.61. The highest agreement rate was in the middle section and the least amount of agreement was related to the apical region.Conclusion: CBCT brand type is not effective factor in the detection of external root resorption. The location and depth of external root resorption can be effective factors in diagnostic accuracy.
外根吸收是一个临床诊断困难的问题,因此影像学检查对诊断很重要。本研究的目的是比较2锥束计算机断层扫描在体外检测外根吸收的诊断准确性。材料与方法:以48颗单根牙为研究对象。在部分根颈、根中、根尖三分之一的颊面、舌面钻孔0.3、0.2、0.15 mm深的圆孔,圆孔0.3 mm。然后进行CBCT扫描,4名观察员评估扫描结果。测定敏感性、特异性和Kappa值。采用z检验进行统计学分析(p值< 0.05)。结果:两种仪器的准确度、灵敏度和特异度比较,无显著差异。在根尖、中段和颈椎以及不同深度,两种装置之间没有显著差异,但从数值上看,两种装置在中段的灵敏度最高。特异性最高的值与根尖区域有关。对于这两种器件,灵敏度等级GBJ,通过增加深度。观察者之间的最低一致性为0.61。一致性率最高的是中部区域,一致性最少的是首都区域。结论:CBCT品牌类型不是检测外牙根吸收的有效因素。外根吸收的位置和深度是影响诊断准确性的重要因素。
{"title":"Comparison of Diagnostic Accuracy of 2 Cone Beam Computed Tomography System (Newtom &Planmeca) for Detection of External Root Resorption in Vitro","authors":"M. Bolbolian, M. Esfehani, N. Hajihassani, Z. Khalili, M. Mobini, M. Tofangchiha","doi":"10.18502/ijds.v18i4.12097","DOIUrl":"https://doi.org/10.18502/ijds.v18i4.12097","url":null,"abstract":"Introduction: External root resorption is a clinical problem that is difficult to diagnose, therefore radiographic examination is important for diagnose. The purpose of this study was comparing the diagnostic accuracy of 2 Cone Beam Computed Tomography in detecting of external root resorption, in vitro.Materials & Methods: This study was done on 48 single-rooted teeth. Cavities of 0.3, 0.2 and 0.15 mm in depth with round bur 0.3 mm were drilled on buccal and lingual surfaces in the cervical, middle and apical thirds of some of roots. Then CBCT were taken and 4 observers assessed the scans. Sensitivity, specificity and Kappa value were determined. The statistical analysis was performed with the Z-test (p value < 0.05).Results: In comparison of the accuracy, sensitivity and specificity of the two devices, there was no significant difference. In the apical, middle and cervical as well as at various depths there was no significant difference between the two devices, but in the numerical point of view, the sensitivity for both devices in the midsection, was in the highest amount. The highest value for the specificity is related to the apical region. For both devices, the sensitivity level GBJ, by increasing the depth. The lowest agreement between observers was 0.61. The highest agreement rate was in the middle section and the least amount of agreement was related to the apical region.Conclusion: CBCT brand type is not effective factor in the detection of external root resorption. The location and depth of external root resorption can be effective factors in diagnostic accuracy.","PeriodicalId":221865,"journal":{"name":"Journal of Isfahan Dental School","volume":"120 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134129382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between the Position of the Mandibular Third Molar with Different Vertical Skeletal Dimensions on the Panoramic Images in Patients Referred to Isfahan (Khorasgan) University Dental School Isfahan (Khorasgan)大学牙科学院转诊患者下颌第三磨牙垂直骨骼尺寸在全景图像上的位置关系
Pub Date : 2023-03-06 DOI: 10.18502/ijds.v18i4.12088
Fateme Eskandari, Nasim Esnaashari, R. Ghaffari, Seyedeh Leila Mousavizadeh Mobarakeh
Introduction: Due to the increased prevalence of third molar impaction and the complications and existence of disagreements regarding the predicting factors for the impaction of this tooth, the aim of this study was to evaluate the relationship between the position of the mandibular third molar with different vertical skeletal dimensions on the panoramic images.Materials & Methods: This cross sectional study was carried out on lateral cephalogram and orthopantomogram records of 130 orthodontic patients visiting to Isfahan (Khorasgan) University Dental School. Age range of the sample was 20-35 years. Various facial forms were determined with mandibular plane angle (SN-GoGn), jarabak index and Y-axis; S-GN– Frankfort plane. Beta angle; which is the angle between intersecting long axis of mandibular second molar and mandibular third molar was measured to determine the angle of eruption of mandibular third molar. Eruption pattern was classified as per Pell & Gregory and winter’s system. The data were analyzed by Chi-square test (p value < 0.05).Results: There was a significant difference in the frequency distribution of growth pattern on the left side of the jaw (p value = 0.048). There was no significant difference in the frequency distribution of the eruption pattern in the right side of the jaw (p value = 0.11). There was no significant difference in the frequency distribution of eruption surface in the right face between different facial forms (p value = 0.49) But on the left side of the jaw there was a significant difference between the three facial forms (p value = 0.049). Frequency distribution of mandibular third molar impaction was significantly different between the three facial forms (p value = 0.03). There was no significant difference between the three facial forms in terms of frequency of eruption angle in the right side of the jaw (p value = 0.25) and also in the left side of the jaw (p value = 0.15).Conclusion: The incidence of impaction was significantly more in patients with long face than in other two groups. The prevalence of surface and pattern of third molar eruption in only one side of jaw was significantly different between the three facial forms. There was no significant difference between the frequency of angle of eruption and facial skeletal types in both jaws.
摘要:由于第三磨牙嵌塞的发病率越来越高,其并发症和对该牙嵌塞的预测因素存在分歧,本研究的目的是评估下颌第三磨牙不同垂直骨骼尺寸在全景图像上的位置关系。材料与方法:对伊斯法罕(霍拉斯甘)大学牙科学院就诊的130例正畸患者的侧位头颅造影和正畸层析成像记录进行横断面研究。样本年龄范围为20-35岁。用下颌平面角(SN-GoGn)、jarabak指数和y轴测定各种面部形态;S-GN -法兰克福飞机。β角;即测量下颌第二磨牙与下颌第三磨牙长轴相交的夹角,确定下颌第三磨牙的出牙角。喷发模式分为Pell & Gregory系统和winter系统。资料采用卡方检验分析(p值< 0.05)。结果:颌左侧生长形态频率分布差异有统计学意义(p值= 0.048)。两组右颌出疹类型的频率分布差异无统计学意义(p值= 0.11)。不同颜面形态间右颜面出疹面频率分布差异无统计学意义(p值= 0.49),而三种颜面形态间左颌出疹面频率分布差异有统计学意义(p值= 0.049)。下颌第三磨牙嵌塞频率分布在三种面部形态间差异有统计学意义(p值= 0.03)。三种颜面形态在右颌和左颌的爆发角频率上差异无统计学意义(p值= 0.25),在左侧的爆发角频率上差异无统计学意义(p值= 0.15)。结论:长脸组嵌塞发生率明显高于其他两组。在三种面部形态中,仅一侧下颌第三磨牙的表面和模式的患病率有显著差异。两颌的出牙角度频率与面部骨骼类型无显著差异。
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引用次数: 0
Effects of Oral Liquid Medicaments in Children on Shear Bond Strength of Resin Composite in Primary Teeth 儿童口服液药物对乳牙树脂复合材料剪切粘结强度的影响
Pub Date : 2023-03-06 DOI: 10.18502/ijds.v18i4.12091
Sara Fotoohi Ashin, Davoud Ghasemi Toodeshkchooie, M. Barekatain
Introduction: Due to the prevalence of the use of oral liquid medications in children with chronic diseases (asthma, heart problems, seizures and kidney problems) and also in children with transient diseases (influenza, colds, tonsillitis, ear infections, sinusitis and seasonal allergy) and due to the fact that several studies have shown that children’s' common medications affect topography and enamel structure, and composite bonding is dependent on enamel structure, the aim of this study was to investigate the effect of oral liquid medications used in children on composite bond strength to primary canine dental enamel.Materials & Methods: In this experimental-laboratory study, 90 teeth were divided into 9 groups, 8 drug groups and 1 control group (artificial saliva). Each group of 10 teeth was immersed 3 times a day for 1 minute in 10 ml of the desired drug. After 7 days and after 14 days, 5 teeth from each group were bonded with composite and their shear bond strengths were measured. Data were analyzed by one-way ANOVA, paired T-test and Pearson correlation coefficient tests. (α = 0.05).Results: In all groups, in comparison with the control group, the mean bond strength was not significantly different in the first and second weeks (p value > 0.05). Also, there was no significant difference between the mean composite shear bond strengths in each of the nine groups in the first and second weeks (p value > 0.05). Pearson correlation coefficient showed that there was no significant relationship between PH value with shear bond strength of composite in first weeks (p value = 0.53) and second (p value = 0.83).Conclusion: Based on this study, short-term use (up to 14 days) of medications did not significantly change the shear bond strength of the composite to enamel.
作品简介:由于患有慢性疾病(哮喘、心脏病、癫痫和肾脏问题)的儿童以及患有短暂性疾病(流感、感冒、扁桃体炎、耳部感染、鼻窦炎和季节性过敏)的儿童普遍使用口服液药物,并且由于若干研究表明,儿童的常用药物影响地形图和牙釉质结构,复合结合依赖于牙釉质结构,本研究的目的是探讨儿童口服液药物对犬初级牙釉质复合结合强度的影响。材料与方法:将90颗牙齿分为9组、8个药物组和1个对照组(人工唾液)。每组10颗牙,每天3次,用所需药物10ml浸泡1分钟。第7天和第14天,每组取5颗牙用复合材料粘结,测定其剪切粘结强度。数据分析采用单因素方差分析、配对t检验和Pearson相关系数检验。(α = 0.05)。结果:与对照组相比,各组第1周和第2周的平均粘结强度差异无统计学意义(p值> 0.05)。各组第1周和第2周的平均复合剪切强度比较,差异均无统计学意义(p值> 0.05)。Pearson相关系数显示,PH值与复合材料第1周(p值= 0.53)和第2周(p值= 0.83)剪切结合强度无显著相关。结论:根据本研究,短期使用(最多14天)药物不会显著改变复合材料与牙釉质的剪切结合强度。
{"title":"Effects of Oral Liquid Medicaments in Children on Shear Bond Strength of Resin Composite in Primary Teeth","authors":"Sara Fotoohi Ashin, Davoud Ghasemi Toodeshkchooie, M. Barekatain","doi":"10.18502/ijds.v18i4.12091","DOIUrl":"https://doi.org/10.18502/ijds.v18i4.12091","url":null,"abstract":"Introduction: Due to the prevalence of the use of oral liquid medications in children with chronic diseases (asthma, heart problems, seizures and kidney problems) and also in children with transient diseases (influenza, colds, tonsillitis, ear infections, sinusitis and seasonal allergy) and due to the fact that several studies have shown that children’s' common medications affect topography and enamel structure, and composite bonding is dependent on enamel structure, the aim of this study was to investigate the effect of oral liquid medications used in children on composite bond strength to primary canine dental enamel.Materials & Methods: In this experimental-laboratory study, 90 teeth were divided into 9 groups, 8 drug groups and 1 control group (artificial saliva). Each group of 10 teeth was immersed 3 times a day for 1 minute in 10 ml of the desired drug. After 7 days and after 14 days, 5 teeth from each group were bonded with composite and their shear bond strengths were measured. Data were analyzed by one-way ANOVA, paired T-test and Pearson correlation coefficient tests. (α = 0.05).Results: In all groups, in comparison with the control group, the mean bond strength was not significantly different in the first and second weeks (p value > 0.05). Also, there was no significant difference between the mean composite shear bond strengths in each of the nine groups in the first and second weeks (p value > 0.05). Pearson correlation coefficient showed that there was no significant relationship between PH value with shear bond strength of composite in first weeks (p value = 0.53) and second (p value = 0.83).Conclusion: Based on this study, short-term use (up to 14 days) of medications did not significantly change the shear bond strength of the composite to enamel.","PeriodicalId":221865,"journal":{"name":"Journal of Isfahan Dental School","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130755148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Odontogenic Tumors Frequency in Biopsies Sent to Isfahan, Shiraz and Yazd Dental Schools 寄往伊斯法罕、设拉子和亚兹德牙科学校的活组织检查对牙源性肿瘤频率的评估
Pub Date : 2023-03-06 DOI: 10.18502/ijds.v18i4.12095
S. M. Razavi, Nafiseh Tadayon, S. Tabatabaei, Z. Jaafari-Ashkavandi, L. Maleki
Introduction: Odontogenic cysts and tumors are lesions found in the upper and lower jaw and oral soft tissue. The understanding and correct diagnosis of odontogenic tumors is essential because they can be invasive or recurrent in nature and even rarely show malignant changes. The aim of this study was to evaluate the frequency of odontogenic tumors in Isfahan, Shiraz and Yazd cites.Materials & Methods: This is a cross-sectional descriptive- analytical study that was performed in the mentioned centers. The records of registered samples from the first year of establishment to 2018 have been reviewed which is approximately 18,000 cases. Samples data were extracted and recorded based on sex, age, jaw and location of involvement in affected jaw. Data were analyzed using descriptive statistics and Chi-square test (p value < 0.05).Results: In this study, a total of 498 odontogenic tumors were evaluated. The number of odontogenic tumors in Isfahan, Shiraz and Yazd cities was 313, 130 and 55, respectively. The mean age of the patients was 30.1 ± 15.9 and most of the patients were in the age group of 20 to 40 years and 53.4% were female. The most common sites of involvement were the right mandibular (29.1%) and then the left mandibular (28.3%) and the most common tumor was ameloblastoma (50.2%) and then complex odontoma (16.7%).Conclusion: Due to the frequency observed for odontogenic tumors, understanding the clinical and pathologic features of these lesions is essential for rapid and appropriate diagnosis and treatment.
牙源性囊肿和肿瘤是在上颚、下颚和口腔软组织中发现的病变。由于牙源性肿瘤具有侵袭性或复发性,甚至很少表现出恶性变化,因此对牙源性肿瘤的认识和正确诊断至关重要。本研究的目的是评估伊斯法罕,设拉子和亚兹德市牙源性肿瘤的频率。材料与方法:这是一项横断面描述性分析研究,在上述中心进行。审查了从成立第一年到2018年的注册样本记录,大约有18,000例。根据患者的性别、年龄、下颌和受累位置提取样本数据并进行记录。资料分析采用描述性统计和卡方检验(p值< 0.05)。结果:本研究共对498例牙源性肿瘤进行了评估。伊斯法罕、设拉子和亚兹德市的牙源性肿瘤数量分别为313例、130例和55例。患者平均年龄为30.1±15.9岁,以20 ~ 40岁年龄组居多,女性占53.4%。最常见的受累部位是右下颌(29.1%),其次是左下颌(28.3%),最常见的肿瘤是成釉细胞瘤(50.2%),其次是复杂牙瘤(16.7%)。结论:牙源性肿瘤发病率高,了解其临床病理特征对快速、准确诊断和治疗至关重要。
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Journal of Isfahan Dental School
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