Chengxiao Zhang, Y. Mu, Ye Zhuo, Taihua Li, F. Jin, Chun-Zhin Jin, Hyung-Gwan Lee, Long Jin
{"title":"Utilizing Bacteria-Derived Components for Cancer Immunotherapy","authors":"Chengxiao Zhang, Y. Mu, Ye Zhuo, Taihua Li, F. Jin, Chun-Zhin Jin, Hyung-Gwan Lee, Long Jin","doi":"10.15212/bioi-2022-0022","DOIUrl":null,"url":null,"abstract":"\n Bacteria-related cancer immunotherapy, because of its mechanisms and useful applications in the induction of anti-tumor immunity, has gained substantial attention in recent decades. Bacteria can enable targeting of tumors, and specifically can colonize the core tumor area. Because they contain many pathogen-associated molecular patterns—which efficiently stimulate immune cells, even within microenvironments that suppress anti-tumor immunity—bacteria boost immunological recognition leading to the destruction of malignant cells. This Editorial highlights various bacteria with immunotherapeutic effects and their by-products used as immunotherapeutics.\n","PeriodicalId":431549,"journal":{"name":"BIO Integration","volume":"66 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"BIO Integration","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15212/bioi-2022-0022","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Bacteria-related cancer immunotherapy, because of its mechanisms and useful applications in the induction of anti-tumor immunity, has gained substantial attention in recent decades. Bacteria can enable targeting of tumors, and specifically can colonize the core tumor area. Because they contain many pathogen-associated molecular patterns—which efficiently stimulate immune cells, even within microenvironments that suppress anti-tumor immunity—bacteria boost immunological recognition leading to the destruction of malignant cells. This Editorial highlights various bacteria with immunotherapeutic effects and their by-products used as immunotherapeutics.
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