{"title":"Bleeding in Dental Surgery","authors":"N. Campos, F. Furlaneto, Y. Buischi","doi":"10.5772/intechopen.89992","DOIUrl":null,"url":null,"abstract":"Excessive bleeding complicates surgery and may result in a higher risk of morbidity in dentistry. Although multiple evidence-based clinical guidelines regard dental interventions as minor procedures, with low risk of bleeding, patients on anticoagulation therapy are at elevated risk of bleeding complications, during and following dental surgeries. In many instances, discontinuation or altering of anticoagulation can be avoided through the use of local hemostatic agents during or after the procedure (or both), while patients are therapeutically continued on their prescribed anticoagulant doses. In addition, patients with diagnosis of hereditary bleeding disorders, such as von Willebrand disease and hemophilia, and individuals without any history of bleeding complications can present the need for the use of topical hemostatic agents. In this chapter, we discuss the mechanisms of action, practical applications, effectiveness, and potential negative effects of biosurgical topical hemostatic agents, such as gelatin sponges, collagen, oxidized regenerated cellulose (ORC) and oxidized cellulose, fibrin sealants, flowables, adhesives, and topical thrombin in dental surgery.","PeriodicalId":127797,"journal":{"name":"Contemporary Applications of Biologic Hemostatic Agents across Surgical Specialties - Volume 2 [Working Title]","volume":"242 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"8","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Contemporary Applications of Biologic Hemostatic Agents across Surgical Specialties - Volume 2 [Working Title]","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5772/intechopen.89992","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 8

Abstract

Excessive bleeding complicates surgery and may result in a higher risk of morbidity in dentistry. Although multiple evidence-based clinical guidelines regard dental interventions as minor procedures, with low risk of bleeding, patients on anticoagulation therapy are at elevated risk of bleeding complications, during and following dental surgeries. In many instances, discontinuation or altering of anticoagulation can be avoided through the use of local hemostatic agents during or after the procedure (or both), while patients are therapeutically continued on their prescribed anticoagulant doses. In addition, patients with diagnosis of hereditary bleeding disorders, such as von Willebrand disease and hemophilia, and individuals without any history of bleeding complications can present the need for the use of topical hemostatic agents. In this chapter, we discuss the mechanisms of action, practical applications, effectiveness, and potential negative effects of biosurgical topical hemostatic agents, such as gelatin sponges, collagen, oxidized regenerated cellulose (ORC) and oxidized cellulose, fibrin sealants, flowables, adhesives, and topical thrombin in dental surgery.
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牙科手术出血
过多的出血使手术复杂化,并可能导致牙科发病率更高的风险。尽管多个循证临床指南将牙科干预视为小手术,出血风险低,但在牙科手术期间和之后,接受抗凝治疗的患者出血并发症的风险较高。在许多情况下,可以通过在手术中或手术后使用局部止血剂(或两者兼而有之)来避免停药或改变抗凝治疗,同时患者继续使用处方剂量的抗凝治疗。此外,诊断为遗传性出血性疾病的患者,如血管性血友病和血友病,以及没有任何出血并发症史的个体,可能需要使用局部止血剂。在本章中,我们讨论了生物外科局部止血剂的作用机制、实际应用、有效性和潜在的负面影响,如明胶海绵、胶原蛋白、氧化再生纤维素(ORC)和氧化纤维素、纤维蛋白密封剂、流动剂、粘合剂和局部凝血酶在牙科手术中的应用。
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