A Feasibility Study of Non-invasive Blood Glucose Level Detection Using Near-Infrared Optical Spectroscopy

Parama Sridevi, A. Arefin, Abu Shahadat Md. Ibrahim
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Abstract

Diabetes mellitus, a common disease of the modern era, is a glucose level disorder in the human body that affects the vital organs of the body and damages them gradually if left untreated. Regular blood glucose monitoring is one of the prescribed routines to control the complications of diabetes. Unfortunately, most available methods of blood glucose level measurement involve invasive ways. Invasive techniques are painful, make the finger skin calloused and the patients suffer from the risk of infectious diseases. Hence, there lies a need to develop an effective non-invasive blood sugar measurement technique to relieve the patients from the nuisance. In order to address the issue, a non-invasive technique has been designed and implemented using 940 nm near-infrared (NIR) LED and a corresponding photodiode. Initially, the in-vitro test was performed over the glucose solution of various concentrations to check the sensitivity of the device. After that pilot experiments were carried out on diabetic patients. The obtained results conformed the theory of near infra-red spectroscopic optical theory. The results also showed that the developed technique can be comparable with the conventional invasive glucometer based method. Furthermore, the implemented prototype is economically viable, especially for the low-income population. This promising results thus pledge the potentials, feasibility, and reliability of the NIR based non-invasive blood glucose detection devices. Bangladesh Journal of Medical Physics Vol.14 No.1 2021 P 1-13
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近红外光谱法无创血糖水平检测的可行性研究
糖尿病是一种现代常见病,是一种影响人体重要器官的血糖水平紊乱,如果不及时治疗,会逐渐损害这些器官。定期血糖监测是控制糖尿病并发症的规定程序之一。不幸的是,大多数可用的血糖测量方法都涉及侵入性方法。侵入性技术是痛苦的,使手指皮肤起茧子,患者有感染传染病的危险。因此,有必要开发一种有效的非侵入性血糖测量技术,以减轻患者的麻烦。为了解决这个问题,我们设计并实现了一种使用940 nm近红外(NIR) LED和相应的光电二极管的非侵入性技术。最初,在不同浓度的葡萄糖溶液中进行体外测试,以检查该装置的灵敏度。之后,对糖尿病患者进行了试点实验。所得结果符合近红外光谱光学理论。结果还表明,所开发的技术可以与传统的侵入性血糖仪方法相媲美。此外,实施的原型在经济上是可行的,特别是对低收入人群。因此,这一有希望的结果保证了基于近红外的无创血糖检测设备的潜力、可行性和可靠性。孟加拉国医学物理杂志Vol.14 no . 2021 P . 1-13
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