Electrochemical Sensing and Biosensor Based on Functional Polymers

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Abstract

Functional polymers has great importance in the field of electrochemical sensing and biosensors due to adaptable chemical, electrical, and structural features, functional polymers are a significant class of materials that have been extensively used to create electrochemical biosensors. Additionally, conducting polymers can be made nanostructured, functional group-grafted chemically, or combined with other functional materials, like nanoparticles, to significantly enhance the sensitivity, selectivity, stability, and reproducibility of the biosensor's response to a variety of bioanalytes. Since these biosensors offer benefits such being affordable and having a low detection limit, they are anticipated to play an increasingly important role in providing diagnostic information and monitoring therapy. Because of this, this article begins with a description of the electroanalytical techniques (amperometry, potentiometry, conductometry, impedometry, voltammetry) used in electrochemical biosensors, and then moves on to a review of recent developments in the use of conducting polymers in the identification of bioanalytes that led to the development of enzyme-based biosensors, immunosensors, DNA biosensors, and whole-cell biosensors.
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基于功能聚合物的电化学传感和生物传感器
功能聚合物在电化学传感和生物传感器领域具有重要意义,由于其具有适应性强的化学、电学和结构特性,功能聚合物是一类重要的材料,已被广泛用于制造电化学生物传感器。此外,导电聚合物可以制成纳米结构,化学接枝官能团,或与其他功能材料(如纳米颗粒)结合,以显着提高生物传感器对各种生物分析物响应的灵敏度,选择性,稳定性和可重复性。由于这些生物传感器具有价格合理、检测限低等优点,预计它们将在提供诊断信息和监测治疗方面发挥越来越重要的作用。因此,本文首先描述了电化学生物传感器中使用的电分析技术(安培法、电位法、电导法、阻抗法、伏安法),然后回顾了在生物分析物鉴定中使用导电聚合物的最新进展,这些进展导致了酶基生物传感器、免疫传感器、DNA生物传感器和全细胞生物传感器的发展。
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