Alcoholism detection markers in blood samples of road users.

M Staak, R Iffland
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Abstract

Alcoholics as participants in road traffic are an international problem. In Germany a confiscated driving licence is only given back by the road traffic authorities to suspected alcoholics after a medico-psychological examination. The problem is: "How can alcoholics be detected among drunken road users." Traffic authorities use as a marker of alcoholism only the height of the blood alcohol concentration. The limit is a level of 1.6 g alcohol per kg blood, in some regions a level of 2.0 g/kg. Our studies show that the blood alcohol level is a very weak marker for alcoholism. Better markers are beside the GGT the alcohols methanol and isopropanol. They can be detected by congener alcohol analysis. Their concentrations are significant elevated by long-lasting drinking like it is typical for alcoholics.

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道路使用者血液样本中的酒精中毒检测标记物。
酗酒者作为道路交通的参与者是一个国际问题。在德国,被没收的驾驶执照只有在经过心理医学检查后才会由道路交通管理部门退还给疑似酗酒者。问题是:“如何在醉酒的道路使用者中发现酗酒者?”交通当局只使用血液酒精浓度作为酒精中毒的标志。酒精含量上限为每公斤血液1.6克,有些地区为每公斤2.0克。我们的研究表明,血液酒精含量是酒精中毒的一个非常弱的标志。较好的标记是在GGT旁边的醇类甲醇和异丙醇。它们可以通过同族醇分析来检测。它们的浓度会因长期饮酒而显著升高,这是酗酒者的典型特征。
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