[Smoking habits in chronic schizophrenics].

K Fukui, T Kobayashi, S Hayakawa, E Koga, S Okazaki, Y Kawashima, F Kawakami, Y Fukui, N Tani, A Kato
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Abstract

The smoking habits of 48 chronic schizophrenics who were inpatients of private psychiatric were examined. Subjects were divided into three groups; non-smokers, moderate smokers and heavy smokers, and tested by Fagerstrom's Tolerance Questionnaire (FTQ) as a tobacco dependence evaluation, and Bender Gestalt Test (BGT) and Benton Visual Retention Test (BVRT) as a neuropsychological battery. In addition, we used the Scales for the Assessment of Negative Symptoms (SANS) to evaluate the degree of schizophrenic negative symptoms, confirming the correlation between SANS score and the amount of nicotine intake or FTQ item. From the results of FTQ scores and their correlation with SANS scores, the amount of nicotine intake was significantly related to the severity of schizophrenic negative symptoms including affective blunting, poverty of thinking and attention impairment. BGT and BVRT showed disturbances in visual-motor gestalt function, and attention and memory, in chronic schizophrenics who smoked, especially in heavy smokers. These results suggest that smoking behavior in chronic schizophrenics might increase the individual vigilance against negative symptoms, from the perspective of self-medication.

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慢性精神分裂症患者的吸烟习惯。
对48例在私立精神病院住院的慢性精神分裂症患者的吸烟习惯进行了调查。受试者被分为三组;非吸烟者、中度吸烟者和重度吸烟者分别采用Fagerstrom耐受性问卷(FTQ)和Bender格式塔测试(BGT)和Benton视觉保留测试(BVRT)作为神经心理测试。此外,我们使用阴性症状评估量表(SANS)来评估精神分裂症阴性症状的程度,证实了SANS评分与尼古丁摄入量或FTQ项目之间的相关性。从FTQ评分及其与SANS评分的相关性来看,尼古丁摄入量与精神分裂症阴性症状的严重程度显著相关,包括情感迟钝、思维贫乏和注意力障碍。吸烟的慢性精神分裂症患者,尤其是重度吸烟者,BGT和BVRT表现出视觉运动完形功能、注意力和记忆的障碍。这些结果表明,从自我药物治疗的角度来看,慢性精神分裂症患者的吸烟行为可能会增加个体对阴性症状的警惕性。
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[Psychiatric studies on alcoholism in Japan]. Early onset of drinking and mortality among male alcoholics. A result of a 10-year prospective follow-up study in Hokkaido, Japan. [Alteration of drinking pattern after the entrance of university]. [Smoking habits in chronic schizophrenics]. [Anabolic steroid abuse and mental disorder].
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