{"title":"Plasmon-enhanced whispering gallery mode biosensing","authors":"F. Vollmer","doi":"10.1109/PGC.2012.6458007","DOIUrl":null,"url":null,"abstract":"Whispering gallery mode (WGM) biosensors derive their unprecedented sensitivity for label-free detection of biomolecules from the high-quality (Q) factor of an optical resonance phenomenon. Plasmonic excitations in metal nanostructures which are able to localize the WGM field at the target binding site can further enhance sensitivity by local electric field amplification. Random nanoparticle layers and nanopost antennas are investigated for this purpose, and an efficiency parameter is introduced to quantitate the local field overlap with analyte molecules, a pre-requisite for single molecule detection.","PeriodicalId":158783,"journal":{"name":"2012 Photonics Global Conference (PGC)","volume":"88 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2012 Photonics Global Conference (PGC)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/PGC.2012.6458007","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Whispering gallery mode (WGM) biosensors derive their unprecedented sensitivity for label-free detection of biomolecules from the high-quality (Q) factor of an optical resonance phenomenon. Plasmonic excitations in metal nanostructures which are able to localize the WGM field at the target binding site can further enhance sensitivity by local electric field amplification. Random nanoparticle layers and nanopost antennas are investigated for this purpose, and an efficiency parameter is introduced to quantitate the local field overlap with analyte molecules, a pre-requisite for single molecule detection.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
