Fluorescence Lifetime Imaging of NADH and FAD in Ex Vivo Young and Old Mouse Cortical Tissue

P. M. Díaz, Narasimhan Rajaram
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Abstract

Young and old murine cortical tissue in fresh, snap frozen, and DMSO-preserved form were investigated with two-photon microscopy. Shorter mean NADH and FAD lifetimes were found in old cortical tissue compared to young.
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离体幼龄和老年小鼠皮质组织中NADH和FAD的荧光寿命成像
用双光子显微镜对新鲜、速冻和dmso保存的幼龄和老年小鼠皮质组织进行了研究。老年皮质组织中NADH和FAD的平均寿命比年轻人短。
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