Genetic manipulation of milk proteins and its consequences for the dairy industry.

Australasian biotechnology Pub Date : 1992-12-01
M J Boland, J P Hill, L K Creamer
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Abstract

Genetic selection of cattle by selective breeding patterns dates back to prehistoric times and has resulted in the diversity of breeds we see today. Selection in New Zealand has been for fat production earlier in the century, and more recently for protein production as well as fat. There is a lot of interest today in the naturally occurring variants of the milk proteins, as these can confer interesting differences in the molecular behaviour of the proteins as well as being correlated with compositional differences in the milk. Genetic modification holds great promise for the future in the dairy industry, but present constraints due to cost, lack of basic knowledge, and difficulty in producing genetically-modified calves, mean that only the biopharmaceutical area is likely to be affected in the near future. Coupled to this is an apparent lack of acceptance of food from genetically-modified animals by consumers. It will therefore need a change in public attitude as well as some development in science and technology before dairy products from genetically modified cattle become a commercial reality.

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牛奶蛋白的基因操纵及其对乳制品工业的影响。
通过选择性育种模式对牛的遗传选择可以追溯到史前时代,并导致了我们今天看到的品种多样性。本世纪初,新西兰的选择一直是为了生产脂肪,最近则是为了生产蛋白质和脂肪。今天,人们对牛奶蛋白质的自然变异很感兴趣,因为这些变异可以赋予蛋白质分子行为上有趣的差异,并与牛奶成分的差异相关联。基因改造在未来的乳制品行业有着巨大的前景,但目前由于成本、缺乏基本知识和生产转基因小牛的困难等限制,意味着在不久的将来只有生物制药领域可能受到影响。与此同时,消费者对转基因动物食品显然缺乏接受度。因此,在转基因牛制成的乳制品成为商业现实之前,公众的态度需要改变,科学技术也需要有所发展。
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