Assessment of Proportion of Radiologically Confirmed Osteoporosis Cases among the Suspected Cases of Female: An Institutional Based Study

P. Pareek, Chandrakala Agarwal, A. K. Mathur
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Abstract

Background: Preventing osteoporosis, a multi factorial disease, resides not only in recognizing its risk factors, but also in identifying potentially modifiable determinants of bone mineral density (BMD), the surrogate measure for osteoporosis. Thus, the present study is designed to assess and compare the risk factors of osteoporosis among women as to prevent osteoporosis, a multi factorial disease, resides not only in recognizing its risk factors, but also in identifying potentially modifiable determinants of bone mineral density (BMD), the surrogate measure for osteoporosis. Subjects and Methods: The present prospective observational analytical study was commenced among 350 females aged between 30-65years who were referred to the Radio diagnosis department as suspected cases of osteoporosis from various outpatient departments. Women in sample after DEXA scan were categorized in two groups; group A comprised women those having normal BMD, considered as control group and group B comprised women with low BMD either osteopenia or osteoporosis included in this group. Datawas collected according to the recommendations of the International Society for Clinical Densitometry.The data collected was compiled, tabulated, analyzed and subjected to Pearson Chi-square test for statistical analysis. Results: While osteoporosis was found to be significantly higher in Low class women (p<0.07) followed by Middle class and upper socioeconomic status. A significant difference was observed between rural and urban people (p<0.01). Women with moderate and low physical activity were significantly at higher risk of osteoporosis. A highly significant difference was observed between two groups in terms of weight, age, BMI, Waist circumference, Hip circumference, BMD lumbar spine, Lumbar Spine T score, Lumbar spine Z score, Femur neck BMD, Femur neck T score & Femur neck Z score whereas there was no significant difference in terms of Height. Conclusion: Within the limits of our study we conclude that osteoporosis is one of the growing concern and need immediate care. The lack of information regarding risk factors for osteoporosis among women is an important problem. Our results highlight the importance of knowledge regarding the risk factors like age, menopausal status, physical activity, smoking, socioeconomic status, geographical location, weight, BMI etc. There is the need for more effective education for the community and medical practitioners for the clinical significance of osteoporotic fractures and its risk factors.
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评估女性疑似病例中影像学证实骨质疏松病例的比例:一项基于机构的研究
背景:骨质疏松是一种多因素疾病,预防骨质疏松不仅在于认识其危险因素,还在于确定骨质疏松的替代指标——骨矿物质密度(BMD)的潜在可改变决定因素。因此,本研究旨在评估和比较女性骨质疏松症的危险因素,以预防骨质疏松症,这是一种多因素疾病,不仅在于认识其危险因素,而且在于确定骨矿物质密度(BMD)的潜在可改变的决定因素,骨质疏松症的替代指标。对象和方法:本前瞻性观察性分析研究开始于350名年龄在30-65岁之间的女性,她们从各个门诊转介到放射科作为骨质疏松的疑似病例。DEXA扫描后的女性样本分为两组;A组由骨密度正常的女性组成,作为对照组,B组由骨密度低的女性组成,包括骨质减少或骨质疏松症。数据是根据国际临床密度测定学会的建议收集的。将收集到的数据进行整理、制表、分析,并进行Pearson卡方检验进行统计分析。结果:社会经济地位低的女性骨质疏松率明显高于社会经济地位低的女性(p<0.07),其次是社会经济地位中高的女性。农村与城市人群间差异有统计学意义(p<0.01)。中等和低体力活动的女性患骨质疏松症的风险明显更高。两组患者在体重、年龄、BMI、腰围、臀围、腰椎骨密度、腰椎T评分、腰椎Z评分、股骨颈骨密度、股骨颈T评分、股骨颈Z评分方面差异均有极显著性,而在身高方面差异无显著性。结论:在我们的研究范围内,我们得出结论,骨质疏松症是一个日益关注的问题,需要立即治疗。缺乏有关妇女骨质疏松症危险因素的信息是一个重要的问题。我们的研究结果强调了年龄、更年期状况、身体活动、吸烟、社会经济地位、地理位置、体重、BMI等风险因素知识的重要性。有必要对社区和医疗从业者进行更有效的教育,以了解骨质疏松性骨折的临床意义及其危险因素。
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