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Osteoid Osteoma of Cuboid Bone- A Rare Cause of Chronic Foot Pain in Childhood –A Case Report 长方体骨类骨瘤——儿童慢性足部疼痛的一种罕见病因
Pub Date : 2020-12-30 DOI: 10.47009/AJMR.2020.9.4.OR1
S. Chaudhary, V. Abdusamad, Aman Verma, V. Garg, R. Siddharth, Vivek Singh
Chronic foot pain in pediatric age group is less common. The usual differential diagnosis may vary from musculoskeletal injury to serious diseases such as osteomyelitis. Benign bone tumor such as osteoid osteoma of foot is exceedingly rare in this age group. Here we present a rare case of osteoid osteoma of cuboid mimicking osteomyelitis. Patient was managed conservatively by Non-steroidal Anti-inflammatory drugs (NSAIDs) with good clinical outcome. Osteoid osteoma of foot bones should be kept in mind in cases with normal blood parameters.
慢性足部疼痛在儿科年龄组是不常见的。通常的鉴别诊断可能从肌肉骨骼损伤到严重的疾病,如骨髓炎。良性骨肿瘤,如足部骨样骨瘤,在这个年龄段极为罕见。我们在此报告一例罕见的长方体骨样骨瘤模拟骨髓炎。患者采用非甾体抗炎药(NSAIDs)保守治疗,临床效果良好。在血液参数正常的情况下,应注意足骨类骨瘤。
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引用次数: 0
A Study on Prevalence of Serum Resistant & Sensitive Escherichia Coli in Urinary Tract Infection 尿路感染血清耐药和敏感大肠杆菌流行病学研究
Pub Date : 2020-12-30 DOI: 10.47009/AJMR.2020.9.4.MB1
K. Prakash, J. Kumar, J. Rajamouli, Sachin Gurnule
Background: Escherichia coli is the commonest organism causing urinary tract infection in women and children especially in those with uncom- plicated infections. It has been traditionally described Serotypes of Escherichia coli were consistently associated with Uropathogenicity and designated as Uropathogenic Escherichia coli.It is now recognized that a subset of fecal Escherichia coli can be colonized in the peri-urethral area, enter the urinary tract and cause symptomatic disease. These are currently defined as Uropathogenic Escherichia coli. The aims & objectives are to the isolation of Escherichia coli in Urinary tract infection. 2. To determine the prevalence of Serum resistant Uropathogenic Escherichia coli. 3. To compare antimicrobial efficacy in Serum resistant and Serum sensitive Uropathogenic Escherichia coli. Subjects & Methods: An observational study was conducted on 100 patients and urine samples collected from suspected and suffering from urinary tract infection. Study period from August 2018 to July 20019 attending General medicine OP in Hospital. Escherichia coli were isolated and identified by conventional techniques Mackie & Mc Cartney. The strains were subjected to multiple drugs to study serum resistance and sensitivity. Results: From 100 urine samples 71 Uropathogenic, 18 males & 53 females. 40% Sero-resistant and 60% Sero-sensitive among them 2 to 18 years males and > 40 years females resistant, above 40 years males and 19 to 40 years females are sensitive to multiple antibiotics. Conclusion: it emphasizes Serum resistance is an important virulence factor, It may lead to pyelonephritis and septicemia. Serum resistant E. coli are multiple drug-resistant, so the present study formulating guidelines for planning effective treatment and Periodic surveillance to monitor resistance.
背景:大肠杆菌是引起妇女和儿童尿路感染的最常见的微生物,特别是在那些无并发症的感染中。传统上,大肠杆菌的血清型与尿路致病性一致,并被指定为尿路致病性大肠杆菌。现在认识到,粪便大肠杆菌的一个亚群可以在尿道周围区域定植,进入尿路并引起症状性疾病。这些目前被定义为尿路致病性大肠杆菌。目的和目的是分离尿路感染中的大肠杆菌。2. 目的:了解血清耐药尿路致病性大肠杆菌的流行情况。3.比较血清耐药与血清敏感尿路致病性大肠杆菌的抗菌效果。对象与方法:对100例疑似尿路感染患者及尿标本进行观察性研究。研究期间为2018年8月至20019年7月在医院全科门诊就诊。采用传统的麦基和麦卡特尼技术对大肠杆菌进行分离鉴定。对该菌株进行多种药物的血清耐药性和敏感性研究。结果:100份尿样71例,男18例,女53例。其中2 ~ 18岁男性、> 40岁女性耐药、40岁以上男性、19 ~ 40岁女性对多种抗生素敏感者占40%、60%。结论:强调血清耐药是肾盂肾炎和败血症的重要毒力因素。血清耐药大肠杆菌具有多重耐药,因此本研究为制定有效治疗计划和定期监测耐药性制定指南。
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引用次数: 0
Study of Influence of Vaginal Ph on the efficacy of Dinoprostone gel for Induction of Labor 阴道Ph值对迪诺前列酮凝胶引产效果影响的研究
Pub Date : 2020-12-30 DOI: 10.47009/AJMR.2020.9.4.OG2
J. Sowmya, T. Krishna
Background: Inducing labor is a procedure intended to trigger artificial contractions of the uterus that generally involve progressive erasure and dilation of the cervix. This will hopefully lead to the birth of a baby through the vaginal route. To assess the efficacy of dinoprostone      gel in cervical maturation and its effect on vaginal pH. Subjects and Methods: The participants were grouped by their vaginal pH into two groups. Group, I included patients with vaginal pH 4.5 and Group II included vaginal pH >4.5 and the differences between the groups with respect to maternal age, parity, gestational age. Those women with minimal change in Bishop Score, received up to 3 doses of dinoprostone gel intracervically, 6 hours apart. Women, who had no change in Bishop Score at the end of induction with 3 doses of dinoprostone, were further reassessed. Results: There was no statistically pertinent relationship between the two groups in regard to maternal age, gestational age, parity, and initial Bishop Score. The mean maternal age in Group I was 25.9 years and Group II was 26.9 years. The mean gestational age was 39.5 weeks in group I and 38.9 weeks in group II. The majority of subjects were primigravidas (70 percent in group I and 63 percent in group II). The mean Bishop score before labor induction was 3.6 0.9 in Group I and 4 1.0 in Group II. Out of 200 cases, 33 (23.3 percent) needed an improvement in Oxytocin, 33 (33.3 percent) in Group I and 4 (13.3 percent) in Group II. The vaginal delivery rate was 90% in Group I and 87% in Group II. The Caesarean section was marginally higher in Group II (10 percent) compared with Group I (13 percent). Conclusion: Parity has a major impact on the pre-induction of the Bishop Score and the pH itself has a vaginal influence. Knowing the pre-induction vaginal pH may also be a helpful method for determining the outcome of PGE2 induction.
背景:引产是一种旨在触发子宫人工收缩的程序,通常涉及子宫颈的渐进清除和扩张。这将有希望通过阴道途径生下一个婴儿。为了评估迪诺前列石凝胶对宫颈成熟的疗效及其对阴道pH值的影响。研究对象和方法:根据阴道pH值将参与者分为两组。第一组阴道pH值为4.5,第二组阴道pH值>4.5,两组产妇年龄、胎次、胎龄的差异。那些Bishop评分变化最小的妇女,每隔6小时在宫颈内注射三剂迪诺前列酮凝胶。在3剂迪诺前列酮诱导结束时Bishop评分无变化的妇女,进一步重新评估。结果:两组在产妇年龄、胎龄、胎次和初始Bishop评分方面无统计学相关性。第一组产妇平均年龄25.9岁,第二组产妇平均年龄26.9岁。ⅰ组平均胎龄39.5周,ⅱ组平均胎龄38.9周。大多数受试者为初迁性(组1占70%,组2占63%)。引产前Bishop平均评分为1组3.6 0.9,2组4 1.0。在200例患者中,需要改善催产素的有33例(23.3%),第一组有33例(33.3%),第二组有4例(13.3%)。第一组阴道分娩率为90%,第二组为87%。第二组的剖腹产率(10%)略高于第一组(13%)。结论:胎次对Bishop评分的预诱导有重要影响,pH值本身对阴道也有影响。了解诱导前阴道pH值也可能是确定PGE2诱导结果的有用方法。
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引用次数: 0
Evaluation of Clinical Profile of Bipolar and Unipolar Depression Patients- A Clinical Study 双相和单相抑郁症患者临床特征的评估-一项临床研究
Pub Date : 2020-12-30 DOI: 10.47009/AJMR.2020.9.4.PY1
M. S. Reddy
Background: The present study was conducted to assess the clinical profile of unipolar and bipolar depressive patients. Subjects & Methods: 74 patients diagnosed with unipolar (40) and bipolar (34) depressive disorders were selected. Depressive cognitions, catatonic features, suicidal thoughts, anhedonia, pseudodementia, dissociative features, panic attacks, delusions, first-rank symptoms, auditory hallucinations, and affective reactivity were recorded. Results: Out of 74 patients, males were 32 and females were 42. Age of onset was 32.2 years in group I and 20.4 years in group II, total duration was 12.4 years in group I and 16.2 years in group II, the number of episodes was 3.4 and 7.1 in group II, the number of hospitalizations was 2.8 in group I and 5.2 in group II, suicidal thoughts were seen in 21 in group I and 24 in group II, anhedonia 10 in group I and 23 in group II, psuedodementia 7 in group I and 13 in group II, dissociative features were seen in 11 in group I and 27 in group II, delusions 4 in group I and 8 in group II, panic symptoms 10 in group I and 18 in group II and auditory hallucination 7 in group I and 18 in group II. The difference was significant (P< 0.05). Conclusion: Authors found that common clinical features were suicidal thoughts, dissociative features, and anhedonia.
背景:本研究旨在评估单极和双相抑郁症患者的临床特征。对象与方法:74例诊断为单相(40例)和双相(34例)抑郁症患者。记录抑郁认知、紧张症特征、自杀念头、快感缺乏、假性痴呆、解离特征、惊恐发作、妄想、一级症状、幻听和情感反应。结果:74例患者中,男32例,女42例。发病的年龄在我组32.2年和20.4年在第二组中,总持续时间在我组12.4年和16.2年在第二组中,事件的数量是3.4和7.1在第二组中,住院的数量是2.8在我组和5.2在第二组中,自杀的念头出现在21组我和24组II,快感缺乏10组我和23组II, psuedodementia 7在第二组我和13组,离解特性被认为在11在第二组我和27组中,ⅰ组妄想4例,ⅱ组8例,ⅰ组惊恐症状10例,ⅱ组18例,ⅰ组幻听7例,ⅱ组18例。差异有统计学意义(P< 0.05)。结论:作者发现常见的临床特征是自杀念头、分离特征和快感缺乏症。
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引用次数: 0
Floor Level Activity as a Sign of Congruency and Containment in Perthes’ Disease 地板水平活动作为Perthes病一致性和遏制的标志
Pub Date : 2020-12-30 DOI: 10.47009/AJMR.2020.9.4.OR2
A. Yadav, W. Thomas, S. Chaudhari, S. Paul
Background: This study aims to note the role of floor level activities like squatting and sitting cross-legged as the indicator of healing with good containment and congruency in Perthes’ disease in children below eight years of age. The research hypothesis of the study is that the functional outcome of the affected hip joint in the form of spontaneous, free and full painless floor level activity in day to day life of the child is a better indicator of outcome irrespective of the radiographic changes in the hip joint. Subjects and Methods: A retrospective observational study  was conducted in a tertiary care university hospital. The study included all the patients diagnosed with Perthes’ disease whose last radiological assessment showed signs of healing. Patients above eight years and patients who had not started showing radiological healing were excluded. Parameters assessed were the presence of lurch, pain at the hip joint, limb length discrepancy, range of motion at the hip joint and ability to sit cross-legged and squat and epiphyseal extrusion index on radiographs. Results: Nineteen hips in 18 patients met criteria with a mean age of 7.1 1.5 years at presentation with a minimum follow-up of 30 (30 – 72) months. None of the patients had any residual lurch or tenderness at  the hip joint at final follow up and all were able to sit cross-legged and squat symmetrically and comfortably with significant improvement of motion at the hip joint (p<0.05). No correlation was noted among the clinical and radiological features; except the internal rotation at healing with epiphyseal extrusion index at healing. Conclusion: Clinical function holds the key primarily in the course of treatment of Legg-Calve-Perthes’ disease. Conservative management in the form of bracing, floor level activities, and hip flexion and abduction exercises lead to congruency and containment in Legg-Calve-Perthes’ disease up to the age of eight years.
背景:本研究旨在注意地板水平活动,如蹲和盘腿坐,作为8岁以下儿童Perthes病良好遏制和一致性愈合的指标的作用。该研究的研究假设是,受影响髋关节的功能结果,以儿童日常生活中自发、自由和完全无痛的活动形式出现,是一个更好的指标,无论髋关节的放射学变化如何。研究对象和方法:在某大学三级医院进行回顾性观察性研究。这项研究包括了所有被诊断为珀尔特斯病的病人,他们最后的放射评估显示出愈合的迹象。八年以上的患者和尚未开始放射治疗的患者被排除在外。评估的参数包括有无午餐、髋关节疼痛、肢体长度差异、髋关节活动范围、盘腿和蹲坐的能力以及x线片上的骨骺挤压指数。结果:18例患者的19个髋关节符合标准,平均年龄为7.1 - 1.5岁,随访时间为30(30 - 72)个月。在最后随访时,所有患者髋关节均无任何残余疼痛或压痛,所有患者均能对称舒适地盘腿坐下和深蹲,髋关节运动明显改善(p<0.05)。临床与影像学表现无相关性;除了愈合时的内旋和愈合时的骨骺挤压指数。结论:临床功能在legg - calf - perthes病的治疗过程中起着关键作用。保守治疗包括支具、地板水平活动、髋关节屈曲和外展练习,可使8岁以下的Legg-Calve-Perthes病保持一致并得到控制。
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引用次数: 0
A Study to Assess the Neurocognitive Profile of Patients with OCD and Depression 强迫症合并抑郁症患者神经认知特征的研究
Pub Date : 2020-12-30 DOI: 10.47009/AJMR.2020.9.4.PY2
M. S. Reddy
Background: The present study was conducted to assess the neurocognitive profile of patients with OCD and depression. Subjects & Methods: It comprised of patients of OCD (42) and depression (42) of both genders. An equal number of healthy control was also recruited. VAIS and performance tests of intelligence (BSS) were recorded. Results: Group I had 22 males and 20 females, group II had 18 males and 24 females and group III had 21 males and 21 females. The value for VAIS and performance tests of intelligence (BSS) parameters such as information were 94.2, 96.4 and 98.3 in all groups respectively, digit span was 103.4, 102.5 and 105.6 in all groups respectively, arithmetic was 95.8, 96.2 and 8.4 in all groups respectively, comprehension was 102.4, 104.5 and 107.3 in all groups respectively, verbal quotient was 105.2 in group I, 103.6 in group II and 10.6.7 in group III respectively. Block design was 9.12, 10.2 and 10.4 in all groups respectively, pass along test was 9.4, 9.8 and 10.2 in all groups respectively and the performance quotient was 102.2, 103.5 and 10.5.7 in all groups respectively. The difference was non-significant (P> 0.05). Conclusion: Neuropsychological/cognitive parameters in patients with OCD, depression and healthy control were comparables.
背景:本研究旨在评估强迫症和抑郁症患者的神经认知特征。对象与方法:强迫症患者42例,抑郁症患者42例,男女均有。同样数量的健康对照也被招募。记录VAIS和BSS智力测验。结果:ⅰ组男性22例,女性20例;ⅱ组男性18例,女性24例;ⅲ组男性21例,女性21例。各组学生的VAIS和信息等智力(BSS)参数得分分别为94.2、96.4和98.3,数字广度得分分别为103.4、102.5和105.6,算术得分分别为95.8、96.2和8.4,理解力得分分别为102.4、104.5和107.3,言语商得分分别为105.2、103.6和10.6.7。各组分块设计分别为9.12、10.2和10.4,各组通过检验分别为9.4、9.8和10.2,各组表现商分别为102.2、103.5和10.5.7。差异无统计学意义(P> 0.05)。结论:强迫症患者、抑郁症患者和健康对照组的神经心理/认知参数具有可比性。
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引用次数: 0
Outcome of Pregnancies with Fibroids and its Associated Complications: A Prospective Study 子宫肌瘤妊娠结局及其相关并发症:一项前瞻性研究
Pub Date : 2020-12-30 DOI: 10.47009/AJMR.2020.9.4.OG1
Swarna Sudha Pullemalla, B. Bhargavi
Background: Fibroids (leiomyomas) are benign smooth muscle cell tumors of the uterus. Although they are extremely common, with an overall incidence of 40% to 60% by age 35 and 70% to 80% by age 50, the precise etiology of uterine fibroids remains unclear. Some studies have shown a relationship between uterine fibroids and pregnancy complications, such as preterm birth, premature rupture of membranes (PROM), fetal malpresentation, placental abruption and intrauterine fetal demise. The aim is to study the outcome of pregnancies with fibroids and their associated complications. Materials and methods: The present study was conducted in the Department of Gynecology in a tertiary care hospital. For the study, a total of 40 patients were selected between the age range of 21 to 45 years from the outpatient list of the department of gynecology with pregnancy with fibroid after attending first-trimester ultrasonography examination which diagnosed them. The patients underwent both consequent antenatal care and delivery at the study institute in the study time. Ultrasonogram was done at successive visits to evaluate the change in the size of the fibroid and any associated complications either in fibroid or in pregnancy in general. Results: We observed that 15 patients had threatened miscarriage, 12 had preterm labor, 2 had antepartum bleeding, 3 had abdominal pain needing admission, 2 had laparotomy due to pain, 1 had a postpartum hemorrhage and only one patient needed a blood transfusion. Spontaneous abortion was observed in 2 patients, premature delivery in 15, delivery at 37-41 weeks in 37, vaginal delivery in 5 patients and cesarean section in 44 patients. Conclusion: Within the limitations of the present study, it can be concluded that pregnant women diagnosed with uterine fibroids are at a greater risk of complication during the antepartum, intrapartum, and postpartum periods.
背景:子宫肌瘤(平滑肌瘤)是良性子宫平滑肌细胞肿瘤。虽然它们非常常见,35岁的总发病率为40%至60%,50岁的总发病率为70%至80%,但子宫肌瘤的确切病因尚不清楚。一些研究表明子宫肌瘤与妊娠并发症,如早产、胎膜早破、胎儿畸形、胎盘早剥和宫内死胎之间存在关系。目的是研究子宫肌瘤妊娠的结局及其相关并发症。材料与方法:本研究在某三级医院妇科进行。本研究选取了40例年龄在21 ~ 45岁之间的妇科门诊就诊的子宫肌瘤妊娠患者,经早期超声检查确诊。在研究期间,患者在研究所接受了相应的产前护理和分娩。在连续就诊时进行超声检查,以评估子宫肌瘤大小的变化以及子宫肌瘤或妊娠的任何相关并发症。结果:有先兆流产15例,早产12例,产前出血2例,腹痛入院3例,因疼痛开腹2例,产后出血1例,需输血1例。自然流产2例,早产15例,37 ~ 41周分娩37例,顺产5例,剖宫产44例。结论:在本研究范围内,诊断为子宫肌瘤的孕妇在产前、产时和产后出现并发症的风险更大。
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引用次数: 1
Assessment of Bacteriological Quality of Drinking Water from Households of Sarvodaya Nagar, Lucknow, Uttar Pradesh, India 印度北方邦勒克瑙Sarvodaya Nagar家庭饮用水细菌质量评估
Pub Date : 2020-12-30 DOI: 10.47009/AJMR.2020.9.4.MB2
S. Srivastava, S. Kashyap, A. Rawat
Background: In the current scenario, the urbanization is happening at a faster pace and the economy is not able to match at par with urbanization, this In turn is causing problems of unavailability of safe and potable water along with proper sewage system, despecially in urban slums. As a result of the scenario many urban slums are still using poor quality pit latrines and even drawing water from nearby wells, water taps which are not complying with government norms. Space is also a big problem which is being faced by these slums, due to which there is a lack of enough spaces in the houses and nearby areas, therby causing overcrowding. Due to overcrowding, the space between houses, pit latrines, wells, taps and water bodies has decreased and thus the potential of contamination of water bodies by fecal microorganisms has increased drastically. Given the above knowledge, a study is much needed to estimate the presumptive and differential coliform count of water samples from the urban slum area in Lucknow. Subjects & Methods: A cross-sectional survey was conducted during the period of January to June 2019. Samples were collected from all the taps, hand pumps that were currently in use, along with potable water stored in households of Sarvodaya Nagar (an urban slum area), Lucknow and were processed in the Microbiology department of IIMS&R, Lucknow. Results: A total of 53(63%) samples were taken from Public supply, out of which 36(67. 9%) were found unsatisfactory and 17(32.0%) were intermediate, were found to be contaminated with Pseudomonas sp., E.coli, Thermotolerent E.coli, Klebsiella Spp. Citrobacter, Enterococcus and Pseudornonas Spp., E.coli, Thermotolerent E.coli, Klebsiella respectively. In the study more than half of the samples were taken from the Public water supply. Out of these about seventy percent were unsatisfactory and were found to be contaminated with Pseudomonas. Conclusion: The proper sanitation, regular treatment, supervision of water sources, arid regular bacteriological assessment of all water sources for drinking should be planned and conducted.
背景:在目前的情况下,城市化正在以更快的速度发生,经济无法与城市化相匹配,这反过来又造成了缺乏安全和饮用水以及适当的污水处理系统的问题,特别是在城市贫民窟。由于这种情况,许多城市贫民窟仍然在使用质量差的坑式厕所,甚至从附近的井里取水,水龙头不符合政府的标准。空间也是这些贫民窟面临的一个大问题,由于房屋和附近地区缺乏足够的空间,从而导致过度拥挤。由于过度拥挤,房屋、坑式厕所、水井、水龙头和水体之间的空间减少了,因此粪便微生物污染水体的可能性急剧增加。鉴于上述知识,非常需要进行一项研究来估计勒克瑙城市贫民窟地区水样的推定和差异大肠菌群计数。对象与方法:于2019年1月至6月进行横断面调查。从勒克瑙Sarvodaya Nagar(城市贫民窟地区)家庭中目前使用的所有水龙头、手动泵以及储存的饮用水中收集样本,并在勒克瑙IIMS&R微生物学部门进行处理。结果:共采集公共供应样本53份(63%),其中36份(67%)。其中,假单胞菌、大肠杆菌、耐高温大肠杆菌、克雷伯氏菌、柠檬酸杆菌、肠球菌和假单胞菌、大肠杆菌、耐高温大肠杆菌、克雷伯氏菌污染不合格的有17个(32.0%)。在这项研究中,超过一半的样本取自公共供水系统。其中约70%不合格,被发现感染了假单胞菌。结论:所有饮用水源应做好卫生、定期处理、监督、定期细菌学评价等工作。
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引用次数: 1
Clinical Profile and Outcome of Patients with Severe Acute Pancreatitis 重症急性胰腺炎患者的临床概况和预后
Pub Date : 2020-10-06 DOI: 10.47009/AJMR.2020.9.3.ME2
R. Sehgal, I. Singh, Jyotisterna Mittal
Background: Acute pancreatitis (AP) is an acute inflammatory condition of the pancreas leading to pancreatic autodigestion. The present study was conducted to study the clinical profile and outcome of patients with severe acute pancreatitis. Subjects & Methods: The study was conducted on 40 patients of acute pancreatitis. Clinical profile including history, examination findings, etiology of pancreatitis, clinical severity (according to Modified Marshall Score, BISAP score, APACHE II, HAPS score, SOFA score) was recorded. Results: Severe Acute Pancreatitis (SAP) among patients. Majority of the patients i.e. 22 (55%) had alcohol consumption as etiological factor causing SAP followed by biliary 10 (25%) & idiopathic 5 (12.5%). Hypertriglyceridemia and drug-induced (herbal medication) pancreatitis was present in 1 (2.5%) patient each. Out of all 1 (2.5%), patients had a history of both alcohol consumption and the presence of gallstone as an etiological factor. 22 patients (55%) out of 40 patients only conservative management was used while 18(45%) patients underwent USG guided percutaneous drainage was done. Out of these 18 patients, 3(7.5%) patients required Laparoscopic Necrosectomy & 2(5%) patients required open necrosectomy in addition to ultrasound-guided PCD. Patients who improved had a mean BISAP SCORE of 2.15   0.54, Modified Marshall score of 3.65    1.44, APACHE II score of 9.77  4.45, SOFA score 5.54  2.49, RANSON’s score 3.85   1.80 and HAP score of 0.65   0.63. Conclusion: Most common   etiology of severe acute pancreatitis is alcohol followed by biliary etiology. Out of severity scores (BISAP, APACHE-II, SOFA, HAPS), only BISAP score ≥3 is predictive of poor outcome in patients with severe acute pancreatitis.
背景:急性胰腺炎(AP)是胰腺的一种急性炎症,导致胰腺自身消化。本研究旨在研究重症急性胰腺炎患者的临床特点和预后。对象与方法:对40例急性胰腺炎患者进行研究。记录临床资料,包括病史、检查结果、胰腺炎病因、临床严重程度(根据改良马歇尔评分、BISAP评分、APACHE II评分、HAPS评分、SOFA评分)。结果:重症急性胰腺炎(SAP)患者。大多数患者22例(55%)以饮酒为SAP的病因,其次是胆道10例(25%)和特发性5例(12.5%)。高甘油三酯血症和药物性(草药)胰腺炎各1例(2.5%)。在所有1例(2.5%)患者中,有饮酒史和作为病因的胆结石存在。40例患者中22例(55%)采用保守治疗,18例(45%)采用USG引导下经皮引流。在这18例患者中,除超声引导下的PCD外,3例(7.5%)患者需要腹腔镜坏死性切除术,2例(5%)患者需要开放式坏死性切除术。改善患者的平均BISAP评分为2.15 0.54,改良Marshall评分为3.65 1.44,APACHE II评分为9.77 4.45,SOFA评分为5.54 2.49,RANSON评分为3.85 1.80,HAP评分为0.65 0.63。结论:重症急性胰腺炎最常见的病因是酒精,其次是胆汁。在严重程度评分(BISAP, APACHE-II, SOFA, HAPS)中,只有BISAP评分≥3可以预测严重急性胰腺炎患者的不良预后。
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引用次数: 0
Assessment of Prevalence and Risk Factors of Dry Eye Disease among Study Group 研究组干眼病患病率及危险因素评估
Pub Date : 2020-10-06 DOI: 10.47009/AJMR.2020.9.3.OT1
Madhavi Chevuturu
Background: Dry eye is a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort, visual disturbance.   The present study was conducted to assess prevalence and risk factors of dry eye diseases among the study group. Subjects and Methods:  The present study was conducted from February 2018 to July 2018 on 184 patients of both genders visiting the Department of Ophthalmology Mediciti institute of medical sciences with eye complaints. Slit-lamp biomicroscopy with a cobalt blue filter was used to investigate the tear film layer, and the interval from the last blink to the appearance of the first random dry spot on the cornea was noted. Schirmer’s test was performed. Whatman filter paper no 41 was placed in the lower fornix at the lateral one-third of the lower lid margin. Results: Age groups 40-50 years had 52, 50-60 years had 98 and 60-70 years had 34 patients. There were 110 males and 74 females. The difference was significant (P< 0.05). 64 (58.1%) males and 40 (54%) had a dry eye disease. The prevalence found to be 61.9%. The severity of DED was mild in 25%, moderate in 46% and severe in 29%. The difference was significant (P< 0.05). Risk factors of DED were steroid use in 14%, smoking in 56%, alcoholism in 24%, computer job in 78%, systemic allergy in 4%, ocular allergy in 32%, contact lens use in 17% and previous ocular surgery in 7%. The difference was significant (P< 0.05). Conclusion: The author found that the prevalence rate of dry eyes was 61.9%. Risk factors of DED were steroid use, smoking, alcoholism, computer job, systemic allergy, ocular allergy, contact lens use and previous ocular surgery.
背景:干眼症是一种多因素的泪液和眼表疾病,可导致不适、视力障碍等症状。本研究旨在评估研究组中干眼病的患病率和危险因素。对象与方法:本研究于2018年2月至2018年7月在医学科学研究所眼科就诊的184例有眼部主诉的男女患者中进行。使用带有钴蓝滤光片的裂隙灯生物显微镜观察泪膜层,并记录从最后一次眨眼到角膜上出现第一个随机干斑的时间间隔。进行Schirmer试验。将第41号Whatman滤纸放在下穹窿下睑缘外侧三分之一处。结果:40 ~ 50岁52例,50 ~ 60岁98例,60 ~ 70岁34例。其中男性110人,女性74人。差异有统计学意义(P< 0.05)。男性64例(58.1%),干眼症40例(54%)。患病率为61.9%。重度DED的25%为轻度,46%为中度,29%为重度。差异有统计学意义(P< 0.05)。DED的危险因素为使用类固醇(14%)、吸烟(56%)、酗酒(24%)、电脑工作(78%)、全身过敏(4%)、眼部过敏(32%)、佩戴隐形眼镜(17%)和既往眼部手术(7%)。差异有统计学意义(P< 0.05)。结论:本组干眼症患病率为61.9%。DED的危险因素为类固醇使用、吸烟、酗酒、电脑工作、全身过敏、眼部过敏、使用隐形眼镜和既往眼部手术。
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Asian Journal of Medical Research
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