M. Bezhenar, M. Drobotenko, A. Svidlov, O. Lyasota, V. V. Tochenaya, A. O. Sulima
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Abstract
In the article, based on the numerical solution of a mechanical mathematical model of the interferon alpha 17 gene and a fragment of the drosophila gene, the influence of the viscosity of the external environment on the dynamics of the DNA molecule and its stability is analyzed. It is shown that an increase in viscosity leads to rapid stabilization of the angular oscillations of nitrogenous bases, and a decrease in viscosity changes the dynamics of DNA: the rate of change in the angular deviations of nitrogenous bases increases and the angular deformations of DNA strands increase at each moment of time.
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