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PATHOPHYSIOLOGICAL FACTORS OF PREMATURE HUMAN AGING 人类早衰的病理生理因素
Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-2-1.127-137
D. Cherkasov, E. N. Petrova
The article discusses methods for increasing human life expectancy.Using MRI, the condition of the muscular corset of the spine was diagnosed with localization of dystrophic manifesta-tions in the vertebrae and intervertebral discs. Osteochondrosis of the spine is considered as premature aging of bone and cartilage tissues caused by spastic conditions in the interverte-bral muscles.
本文讨论了延长人类预期寿命的方法。通过MRI,诊断脊柱肌肉束腹的状况为椎骨和椎间盘的局部营养不良表现。脊柱骨性软骨病被认为是由椎间肌痉挛引起的骨和软骨组织过早老化。
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引用次数: 0
PROBLEMS OF SPACE BIOLOGY AND GENETICS 空间生物学和遗传学问题
Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-2-1.113-118
M. Aslanyan
The article discusses the main problems and stages of the development of space biology, med-icine and genetics. Biological tests on different species of animals and plants, in the conditions of space flight, allowed scientists to predict the safety of human flight into space. The existence of a negative influence of space factors on biological processes and morphophysiological structure of organisms requires further research to ensure the biological safety of a long-term human stay in space.
本文论述了空间生物学、空间医学和空间遗传学发展的主要问题和阶段。在太空飞行条件下对不同种类的动物和植物进行生物试验,使科学家能够预测人类进入太空飞行的安全性。空间因素对生物过程和生物形态生理结构的负面影响需要进一步研究,以确保人类长期停留在空间的生物安全。
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引用次数: 0
DEVELOPMENT AND FUNCTION OF THE ADRENAL MEDULLA IN EXPOSED TO ENDOCRINE DISRUPTOR DDT ORGANISMS 暴露于内分泌干扰物DDT生物的肾上腺髓质的发育和功能
Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-2-1.119-123
N. Yaglova
Development and function of the adrenal medulla in exposed to endocrine disruptor DDT organisms was studied. The investigation revealed disrupted by DDT morphogenesis and se-cretion of adrenal medulla resulted in decreased production of catecholamines.
研究了内分泌干扰物DDT对肾上腺髓质发育和功能的影响。研究发现,DDT破坏肾上腺髓质的形态发生和分泌,导致儿茶酚胺的产生减少。
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引用次数: 0
PROSPECTS FOR THE USE OF ISOTOPE-MODIFIED WATER IN BIOLOGY AND MEDICINE 同位素改性水在生物和医学中的应用前景
Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-2-1.87-91
V. Lobyshev
The review gives a brief history of the study of biological isotopic effects associated with the replacement of H2O by D2O, explains the quantum nature of kinetic and thermodynamic iso-topic effects of deuterium, as well as isotopic effects of heavy water as a solvent. Some possible medical applications are considered.
本文简要介绍了与水被D2O取代相关的生物同位素效应的研究历史,解释了氘的动力学和热力学同位素效应的量子性质,以及重水作为溶剂的同位素效应。考虑了一些可能的医疗应用。
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引用次数: 0
REACTIVE AND COMPENSATORY CHANGES IN PITUITARY-THYROID AXIS INDUCED BY REDUCED INTAKE OF DEUTERIUM 氘摄入减少引起垂体-甲状腺轴的反应性和代偿性改变
Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-2-1.101-104
E. Timokhina, S. Obernikhin, N. Yaglova
The paper represents the results of the investigation aimed at elucidation of reactive and com-pensatory changes in pituitary-thyroid axis induced by reduced intake of deuterium, which indicate that both types of changes were developed in peripheral part of the axis.
本文报道了由氘摄入减少引起的垂体-甲状腺轴反应性和代偿性变化的研究结果,表明这两种变化都发生在垂体-甲状腺轴的外周部分。
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引用次数: 0
INFLUENCE OF SUBSTANCES ON FORMATION OF THERMOLIPOFUSCIN 物质对热褐素形成的影响
Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-2-1.384-389
V. Kovalev, D. Zhdanova, N. Bobkova, A. Chaplygina
The paper discusses one of the pigments of aging and pathological processes, including neu-rodegenerative ones - lipofuscin, as well as a model for its accelerated production and deg-radation methods. Original experiments on the effect of substances of different chemical na-ture on the formation of lipofuscin from rat liver mitochondria are presented.
本文讨论了一种衰老和病理过程的色素,包括新退行性色素-脂褐素,以及它的加速生产和降解方法的模型。本文介绍了不同化学性质的物质对大鼠肝脏线粒体脂褐素形成影响的原始实验。
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引用次数: 0
«STRUCTURE – ACTIVITY» RELATIONSHIP OF ANTIARRHYTHMIC DRUGS NIBENTAN AND NIFERIDYL 抗心律失常药物尼本坦和硝维啶的结构-活性关系
Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-2-1.123-126
N. Davydova
The paper summarizes data on the relationship between the chemical structure of nibentan and niferidyl pharmaceutical ingredients and their antiarrhythmic activity.
本文综述了尼本坦和硝基类药物成分的化学结构与抗心律失常活性之间的关系。
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引用次数: 0
ISSUES OF HEALTH RISK ANALYSIS OF FOOD OBTAINED BY MICROBIAL SYNTHESIS 微生物合成食品的健康风险分析问题
Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-2-1.57-63
O. Bagryantseva, Z. Gureu
The article provides suggestions on the procedure for conducting risk analysis of technological strains of microorganisms and food obtained with their use, based on data from in vivo and in vitro experiments.
本文根据体内和体外实验数据,对微生物工艺菌株及其所获得的食品进行风险分析的程序提出了建议。
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引用次数: 0
ANALYSIS OF MORPHOLOGICAL CHANGES OF TESTES AFTER γ- IRRADIA-TION γ辐照后睾丸形态变化分析
Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-2-1.183-184
M. A. Al Meselmani, N. Glinskaya
We studied the effects of radiation in small doses (0.5 Gy) on the spermatogenic epithelium of white rats, counted the number of transversely cut convoluted seminiferous tubules, and de-termined the types of tubules. A decrease in the number of seminiferous tubules was noted, with damage to the cells of the spermatogenic epithelium.
我们研究了小剂量(0.5 Gy)辐射对大鼠生精上皮的影响,统计了横切曲精小管的数量,并确定了小管的类型。精子小管数量减少,生精上皮细胞受损。
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引用次数: 0
POLYPHASE APPROACH FOR SPECIES IDENTIFICATION OF MICROMY-CETES - FOOD CONTAMINANTS 食品污染物微生物种类鉴定的多相法
Pub Date : 1900-01-01 DOI: 10.47501/978-5-6044060-2-1.19-24
L. P. Minaeva, Y. Markova, A. D. Evsjukova
The article presents an integrated approach based on polyphasic taxonomy, which includes the study of phenotypic, molecular genetic and chemotaxonomic characteristics of micromycetes. This approach makes it possible to obtain reliable results of species identification of mold con-taminants in food products, to expand knowledge about the metabolite profiles of specific fungal species and their chemotypes. The potential for the formation of mycotoxins (MT) by mold con-taminants of the genus Aspergillus isolated from coffee raw materials has been shown. It was shown that, under favorable conditions, they are able to simultaneously accumulate several dangerous MTs (OTA, AFL B1, FB2), as well as emergent MT (STC).
本文介绍了一种基于多相分类学的综合方法,包括对微菌的表型、分子遗传和化学分类特征的研究。该方法可以获得可靠的食品中霉菌污染物种类鉴定结果,扩大对特定真菌种类及其化学型的代谢谱的了解。从咖啡原料中分离出的曲霉菌属的霉菌污染物可能形成霉菌毒素(MT)。结果表明,在有利条件下,它们能够同时积累几种危险MT (OTA、AFL B1、FB2)和紧急MT (STC)。
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引用次数: 0
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