Pub Date : 1900-01-01DOI: 10.47501/978-5-6044060-2-1.127-137
D. Cherkasov, E. N. Petrova
The article discusses methods for increasing human life expectancy.Using MRI, the condition of the muscular corset of the spine was diagnosed with localization of dystrophic manifesta-tions in the vertebrae and intervertebral discs. Osteochondrosis of the spine is considered as premature aging of bone and cartilage tissues caused by spastic conditions in the interverte-bral muscles.
{"title":"PATHOPHYSIOLOGICAL FACTORS OF PREMATURE HUMAN AGING","authors":"D. Cherkasov, E. N. Petrova","doi":"10.47501/978-5-6044060-2-1.127-137","DOIUrl":"https://doi.org/10.47501/978-5-6044060-2-1.127-137","url":null,"abstract":"The article discusses methods for increasing human life expectancy.Using MRI, the condition of the muscular corset of the spine was diagnosed with localization of dystrophic manifesta-tions in the vertebrae and intervertebral discs. Osteochondrosis of the spine is considered as premature aging of bone and cartilage tissues caused by spastic conditions in the interverte-bral muscles.","PeriodicalId":154149,"journal":{"name":"Conference Proccedings NT+ME'22","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116886829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.47501/978-5-6044060-2-1.113-118
M. Aslanyan
The article discusses the main problems and stages of the development of space biology, med-icine and genetics. Biological tests on different species of animals and plants, in the conditions of space flight, allowed scientists to predict the safety of human flight into space. The existence of a negative influence of space factors on biological processes and morphophysiological structure of organisms requires further research to ensure the biological safety of a long-term human stay in space.
{"title":"PROBLEMS OF SPACE BIOLOGY AND GENETICS","authors":"M. Aslanyan","doi":"10.47501/978-5-6044060-2-1.113-118","DOIUrl":"https://doi.org/10.47501/978-5-6044060-2-1.113-118","url":null,"abstract":"The article discusses the main problems and stages of the development of space biology, med-icine and genetics. Biological tests on different species of animals and plants, in the conditions of space flight, allowed scientists to predict the safety of human flight into space. The existence of a negative influence of space factors on biological processes and morphophysiological structure of organisms requires further research to ensure the biological safety of a long-term human stay in space.","PeriodicalId":154149,"journal":{"name":"Conference Proccedings NT+ME'22","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127118580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.47501/978-5-6044060-2-1.119-123
N. Yaglova
Development and function of the adrenal medulla in exposed to endocrine disruptor DDT organisms was studied. The investigation revealed disrupted by DDT morphogenesis and se-cretion of adrenal medulla resulted in decreased production of catecholamines.
{"title":"DEVELOPMENT AND FUNCTION OF THE ADRENAL MEDULLA IN EXPOSED TO ENDOCRINE DISRUPTOR DDT ORGANISMS","authors":"N. Yaglova","doi":"10.47501/978-5-6044060-2-1.119-123","DOIUrl":"https://doi.org/10.47501/978-5-6044060-2-1.119-123","url":null,"abstract":"Development and function of the adrenal medulla in exposed to endocrine disruptor DDT organisms was studied. The investigation revealed disrupted by DDT morphogenesis and se-cretion of adrenal medulla resulted in decreased production of catecholamines.","PeriodicalId":154149,"journal":{"name":"Conference Proccedings NT+ME'22","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125407540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.47501/978-5-6044060-2-1.87-91
V. Lobyshev
The review gives a brief history of the study of biological isotopic effects associated with the replacement of H2O by D2O, explains the quantum nature of kinetic and thermodynamic iso-topic effects of deuterium, as well as isotopic effects of heavy water as a solvent. Some possible medical applications are considered.
{"title":"PROSPECTS FOR THE USE OF ISOTOPE-MODIFIED WATER IN BIOLOGY AND MEDICINE","authors":"V. Lobyshev","doi":"10.47501/978-5-6044060-2-1.87-91","DOIUrl":"https://doi.org/10.47501/978-5-6044060-2-1.87-91","url":null,"abstract":"The review gives a brief history of the study of biological isotopic effects associated with the replacement of H2O by D2O, explains the quantum nature of kinetic and thermodynamic iso-topic effects of deuterium, as well as isotopic effects of heavy water as a solvent. Some possible medical applications are considered.","PeriodicalId":154149,"journal":{"name":"Conference Proccedings NT+ME'22","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125517054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.47501/978-5-6044060-2-1.101-104
E. Timokhina, S. Obernikhin, N. Yaglova
The paper represents the results of the investigation aimed at elucidation of reactive and com-pensatory changes in pituitary-thyroid axis induced by reduced intake of deuterium, which indicate that both types of changes were developed in peripheral part of the axis.
{"title":"REACTIVE AND COMPENSATORY CHANGES IN PITUITARY-THYROID AXIS INDUCED BY REDUCED INTAKE OF DEUTERIUM","authors":"E. Timokhina, S. Obernikhin, N. Yaglova","doi":"10.47501/978-5-6044060-2-1.101-104","DOIUrl":"https://doi.org/10.47501/978-5-6044060-2-1.101-104","url":null,"abstract":"The paper represents the results of the investigation aimed at elucidation of reactive and com-pensatory changes in pituitary-thyroid axis induced by reduced intake of deuterium, which indicate that both types of changes were developed in peripheral part of the axis.","PeriodicalId":154149,"journal":{"name":"Conference Proccedings NT+ME'22","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114162525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.47501/978-5-6044060-2-1.384-389
V. Kovalev, D. Zhdanova, N. Bobkova, A. Chaplygina
The paper discusses one of the pigments of aging and pathological processes, including neu-rodegenerative ones - lipofuscin, as well as a model for its accelerated production and deg-radation methods. Original experiments on the effect of substances of different chemical na-ture on the formation of lipofuscin from rat liver mitochondria are presented.
{"title":"INFLUENCE OF SUBSTANCES ON FORMATION OF THERMOLIPOFUSCIN","authors":"V. Kovalev, D. Zhdanova, N. Bobkova, A. Chaplygina","doi":"10.47501/978-5-6044060-2-1.384-389","DOIUrl":"https://doi.org/10.47501/978-5-6044060-2-1.384-389","url":null,"abstract":"The paper discusses one of the pigments of aging and pathological processes, including neu-rodegenerative ones - lipofuscin, as well as a model for its accelerated production and deg-radation methods. Original experiments on the effect of substances of different chemical na-ture on the formation of lipofuscin from rat liver mitochondria are presented.","PeriodicalId":154149,"journal":{"name":"Conference Proccedings NT+ME'22","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114508134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.47501/978-5-6044060-2-1.123-126
N. Davydova
The paper summarizes data on the relationship between the chemical structure of nibentan and niferidyl pharmaceutical ingredients and their antiarrhythmic activity.
本文综述了尼本坦和硝基类药物成分的化学结构与抗心律失常活性之间的关系。
{"title":"«STRUCTURE – ACTIVITY» RELATIONSHIP OF ANTIARRHYTHMIC DRUGS NIBENTAN AND NIFERIDYL","authors":"N. Davydova","doi":"10.47501/978-5-6044060-2-1.123-126","DOIUrl":"https://doi.org/10.47501/978-5-6044060-2-1.123-126","url":null,"abstract":"The paper summarizes data on the relationship between the chemical structure of nibentan and niferidyl pharmaceutical ingredients and their antiarrhythmic activity.","PeriodicalId":154149,"journal":{"name":"Conference Proccedings NT+ME'22","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116731262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.47501/978-5-6044060-2-1.57-63
O. Bagryantseva, Z. Gureu
The article provides suggestions on the procedure for conducting risk analysis of technological strains of microorganisms and food obtained with their use, based on data from in vivo and in vitro experiments.
本文根据体内和体外实验数据,对微生物工艺菌株及其所获得的食品进行风险分析的程序提出了建议。
{"title":"ISSUES OF HEALTH RISK ANALYSIS OF FOOD OBTAINED BY MICROBIAL SYNTHESIS","authors":"O. Bagryantseva, Z. Gureu","doi":"10.47501/978-5-6044060-2-1.57-63","DOIUrl":"https://doi.org/10.47501/978-5-6044060-2-1.57-63","url":null,"abstract":"The article provides suggestions on the procedure for conducting risk analysis of technological strains of microorganisms and food obtained with their use, based on data from in vivo and in vitro experiments.","PeriodicalId":154149,"journal":{"name":"Conference Proccedings NT+ME'22","volume":"192 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121738090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.47501/978-5-6044060-2-1.183-184
M. A. Al Meselmani, N. Glinskaya
We studied the effects of radiation in small doses (0.5 Gy) on the spermatogenic epithelium of white rats, counted the number of transversely cut convoluted seminiferous tubules, and de-termined the types of tubules. A decrease in the number of seminiferous tubules was noted, with damage to the cells of the spermatogenic epithelium.
{"title":"ANALYSIS OF MORPHOLOGICAL CHANGES OF TESTES AFTER γ- IRRADIA-TION","authors":"M. A. Al Meselmani, N. Glinskaya","doi":"10.47501/978-5-6044060-2-1.183-184","DOIUrl":"https://doi.org/10.47501/978-5-6044060-2-1.183-184","url":null,"abstract":"We studied the effects of radiation in small doses (0.5 Gy) on the spermatogenic epithelium of white rats, counted the number of transversely cut convoluted seminiferous tubules, and de-termined the types of tubules. A decrease in the number of seminiferous tubules was noted, with damage to the cells of the spermatogenic epithelium.","PeriodicalId":154149,"journal":{"name":"Conference Proccedings NT+ME'22","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133492733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.47501/978-5-6044060-2-1.19-24
L. P. Minaeva, Y. Markova, A. D. Evsjukova
The article presents an integrated approach based on polyphasic taxonomy, which includes the study of phenotypic, molecular genetic and chemotaxonomic characteristics of micromycetes. This approach makes it possible to obtain reliable results of species identification of mold con-taminants in food products, to expand knowledge about the metabolite profiles of specific fungal species and their chemotypes. The potential for the formation of mycotoxins (MT) by mold con-taminants of the genus Aspergillus isolated from coffee raw materials has been shown. It was shown that, under favorable conditions, they are able to simultaneously accumulate several dangerous MTs (OTA, AFL B1, FB2), as well as emergent MT (STC).
{"title":"POLYPHASE APPROACH FOR SPECIES IDENTIFICATION OF MICROMY-CETES - FOOD CONTAMINANTS","authors":"L. P. Minaeva, Y. Markova, A. D. Evsjukova","doi":"10.47501/978-5-6044060-2-1.19-24","DOIUrl":"https://doi.org/10.47501/978-5-6044060-2-1.19-24","url":null,"abstract":"The article presents an integrated approach based on polyphasic taxonomy, which includes the study of phenotypic, molecular genetic and chemotaxonomic characteristics of micromycetes. This approach makes it possible to obtain reliable results of species identification of mold con-taminants in food products, to expand knowledge about the metabolite profiles of specific fungal species and their chemotypes. The potential for the formation of mycotoxins (MT) by mold con-taminants of the genus Aspergillus isolated from coffee raw materials has been shown. It was shown that, under favorable conditions, they are able to simultaneously accumulate several dangerous MTs (OTA, AFL B1, FB2), as well as emergent MT (STC).","PeriodicalId":154149,"journal":{"name":"Conference Proccedings NT+ME'22","volume":"151 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131277254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}