Prediction of Embolic Events in Infective Endocarditis Using Echocardiography

L. Iliuță
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Abstract

Aim: Defining the echographic parameters which can help in identifying the high-risk groups for embolic events (EE) in patients with infective endocarditis (IE). Material and method: 236 patients with IE followed up 3 years with ECO parameters measured on the vegetations (VEG). Results: (1) the incidence rate of the EE was 51.27% without any significant differences for EE occurrence from the point of view of clinical parameters. (2) There was a significant correlation between the embolia occurrence and IE with staphylococcus, IE of the right heart, the length and mobility of VEG. The only independent predictors for EE were: the maximum length >15 mm and the increased mobility of VEG with the maximal angle >60.7. (3) In 23.14% of the patients with big and very mobile, EE occurred after starting the antibiotic treatment. Conclusions: (1) the VEG dimension and mobility determined by TEE are important predictors for the prognostic and are cor- related with the embolic risk. (2) Significant ECO predictors of the EE occurrence were: VEG length >15 mm, neck/thickness ratio >0.69, and maximal angle of displacement of VEG in the cardiac cycle >60.7. (3) During the antibiotic treatment, the embolic risk depends only on VEG mobility and dimension.
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超声心动图预测感染性心内膜炎栓塞事件
目的:确定感染性心内膜炎(IE)患者栓塞事件(EE)高危人群的超声参数。材料与方法:对236例IE患者进行为期3年的随访,测量其植被(VEG)的ECO参数。结果:(1)两组患者情感表达发生率为51.27%,从临床参数上看,情感表达发生率无显著差异。(2)葡萄球菌、右心IE、VEG长度和活动性与栓塞发生有显著相关性。EE的独立预测因子为:最大长度>15 mm,最大角度>60.7的VEG迁移率增加。(3) 23.14%的大且活动能力很强的患者EE发生在开始抗生素治疗后。结论:(1)TEE测定的VEG尺寸和流动性是预测预后的重要指标,与栓塞风险密切相关。(2) VEG长度>15 mm、颈厚比>0.69、心周期VEG最大位移角>60.7是EE发生的ECO显著预测因子。(3)在抗生素治疗期间,栓塞风险仅取决于血管内皮细胞的流动性和大小。
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